Description
LY-3177833 is an inhibitor of Cdc7, a therapeutic target for some cancers. It slows tumor growth in human colorectal adenocarcinoma cell lines in vitro.
Product Unit Size | Cost | Quantity | Stock |
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LY-3177833 is an inhibitor of Cdc7, a therapeutic target for some cancers. It slows tumor growth in human colorectal adenocarcinoma cell lines in vitro.
Cas No. | 1627696-51-8 |
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Purity | ≥99% |
Formula | C16H12FN5O |
Formula Wt. | 309.30 |
Chemical Name | LY-3177833 |
IUPAC Name | (3R)-3-(5-Fluoro-4-pyrimidinyl)-3-methyl-6-(1H-pyrazol-4-yl)-1-isoindolinone |
Synonym | LY 3177833, LY3177833 |
Store Temp | -20°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Cheng A., Lo Y., et al. Identification of Novel Cdc7 Kinase Inhibitors as Anti-Cancer Agents that Target the Interaction with Dbf4 by the Fragment Complementation and Drug Repositioning Approach. EBioMedicine. 36:241-251 (2018). PMID: 30293817.
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