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Lysipressin is a pressor peptide found in marsupials and pigs that binds to VP receptors, which are analogous to human Vasopressin 2 (V2) receptors. Lysipressin induces contractions in smooth muscle and potentiates effects of gastric lesioning in animal models.
| Cas No. | 50-57-7 |
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| Purity | ≥95% |
| Formula | C46H65N13O12S2 |
| Formula Wt. | 1056.22 |
| IUPAC Name | acetic acid;N-[6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide |
| Synonym | Lypressin, (8-Lysine)vasopressin, Diapid, Pitressin, Postacton, Syntopressin, Vasophysin |
| Solubility | Soluble in 0.1 M acetic acid (20 mg/mL), water (0.9 mg/mL). |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
László F, Karácsony G, Pávó I, et al. Aggressive role of vasopressin in development of different gastric lesions in rats. Eur J Pharmacol. 1994 Jun 2;258(1-2):15-22. PMID: 7925594.
Gorbulev V, Büchner H, Akhundova A, et al. Molecular cloning and functional characterization of V2 [8-lysine] vasopressin and oxytocin receptors from a pig kidney cell line. Eur J Biochem. 1993 Jul 1;215(1):1-7. PMID: 8393786.
Crankshaw D. [Arg8]vasopressin-induced contractions of rabbit urinary bladder smooth muscle. Eur J Pharmacol. 1989 Dec 7;173(2-3):183-8. PMID: 2625135.
Acher R, Chauvet J. Structure, processing and evolution of the neurohypophysial hormone-neurophysin precursors. Biochimie. 1988 Sep;70(9):1197-207. PMID: 3147712.