• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Met-Enkephalin Amide

Met-Enkephalin Amide

Product ID E2542
Cas No. 60117-17-1
Purity ≥95%
Product Unit SizeCostQuantityStock
10 mg $85.90 In stock
20 mg $142.90 In stock
50 mg $253.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Met-enkephalin is an endogenous opioid peptide that acts as an agonist at μ-opioid receptors (μORs) and δ-opioid receptors (δORs). Met-enkephalin exhibits neuromodulatory, antinociceptive/analgesic, antidepressant, and gastrointestinal motility modulating activities. Like other endogenous opioids, met-enkephalin modulates expression of opioid receptors and plays a role in reward/reinforcement signaling. Met-enkephalin is also involved in exercise-induced reversal of neuropathic pain and in animals undergoing the forced swim test, decreases immobility time. Met-enkephalin inhibits gastrointestinal muscle contractility, inhibiting motility and gastric emptying. Additionally, analogs of this peptide display anticancer and antiepileptic/anticonvulsant activities.

Product Info

Cas No.

60117-17-1

Purity

≥95%

Formula

C27H36N6O6S

Formula Wt.

572.69

IUPAC Name

(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanamide

Synonym

Enkephalinamide-met-, Methionine enkephalinamide

Solubility

Soluble in water.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

E2542 MSDS PDF

Info Sheet

E2542 Info Sheet PDF

References

Gonzalez-Nunez V, Jimenez González A, Barreto-Valer K, et al. In vivo regulation of the μ opioid receptor: role of the endogenous opioid agents. Mol Med. 2013 Mar 5;19:7-17. PMID: 23348513.

Fanning RA, McMorrow JP, Campion DP, et al. Opioid mediated activity and expression of mu and delta opioid receptors in isolated human term non-labouring myometrium. Eur J Pharmacol. 2013 Jan 5;698(1-3):170-7. PMID: 23051674.

Hadjiconstantinou M, Neff NH. Nicotine and endogenous opioids: neurochemical and pharmacological evidence. Neuropharmacology. 2011 Jun;60(7-8):1209-20. PMID: 21108953.

Stagg NJ, Mata HP, Ibrahim MM, et al. Regular exercise reverses sensory hypersensitivity in a rat neuropathic pain model: role of endogenous opioids. Anesthesiology. 2011 Apr;114(4):940-8. PMID: 21386701.

Gredicak M, Supek F, Kralj M, et al. Computational structure-activity study directs synthesis of novel antitumor enkephalin analogs. Amino Acids. 2010 Apr;38(4):1185-91. PMID: 19639251.

Lee HK, Smith MD, Smith BJ, et al. Anticonvulsant Met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain. ACS Chem Biol. 2009 Aug 21;4(8):659-71. PMID: 19634861.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C5260

    C-type Natriuretic Peptide (1-22), pig/human/rat

    Endogenous cardiomodulatory peptide; NPR-B agon...

    ≥95%
  • L8010

    D-Luciferin Potassium

    Heterocyclic light-emitting compound, natural l...

    ≥98%
  • T6931

    Triclosan

    Diarylether; bacterial ENR binder, fatty acid s...

    ≥98%
  • V9202

    VX-702

    p38 MAPK inhibitor.

    ≥98%
  • D1749

    Demecolcine

    Used to study embryonic cloning; microtubule po...

    ≥97%
  • F3207

    Fibronectin CS-1 Peptide

    Peptide; α4β1 integrin activator.

    ≥95%
  • F130280

    FHD-286

    BRG1/BRM ATPase inhibitor

    ≥98%
  • P1622

    Pefloxacin Methanesulfonate Dihydrate

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • C6957

    Croton Oil

    Mixture found in Croton, used to induce inflamm...

  • A4675

    Alternariol

    Mycotoxin produced by Alternaria; topoisomerase...

    ≥98%
  • S1607

    Secretin, rat

    Endogenous peptide hormone, involved in feeding...

    ≥95%
  • E5358

    Enoxacin

    Fluoroquinolone; vacuolar H+ ATPase, topoisomer...

    ≥98%
  • C3576

    Citreoviridin A

    Mycotoxin; F1F0 ATP synthase inhibitor.

    ≥95%
  • D3447

    Diltiazem Hydrochloride

    Benzothiazepine; L-type Ca2+ channel blocker, p...

    ≥98%
  • F5874

    Fosfomycin Calcium

    MurA and isopentenyl mevalonate kinase inhibito...

    ≥95%
  • P0092

    Paclitaxel, from Taxus yunnanensis

    Diterpene found in Taxus yunnanensis; microtubu...

    ≥98%
  • I5354

    Iniparib

    Cysteine adduct inducer, PARP-1 inhibitor.

    ≥98%
  • G1646

    Geldanamycin

    HSP90 inhibitor.

    ≥97%
  • D0261

    Dapivirine

    RT inhibitor.

    ≥98%
  • F4518

    Fleroxacin

    Fluoroquinolone; bacterial DNA gyrase and helic...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only