• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
NVP-BGT226

NVP-BGT226

Product ID N8604
Cas No. 1245537-68-1
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $155.00 In stock
5 mg $455.70 In stock
10 mg $729.30 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

NVP-BGT226 is an inhibitor of PI3K and mTORC1/2. An intracellular Leishmania parasite assay found it to be even more potent than amphotericin B or miltefosine. In a mouse model of T. brucei acute infection, NVP-BGT226 showed slightly improved effiecacy compared to Torin2.

Product Info

Cas No.

1245537-68-1

Purity

≥98%

Formula

C32H29F3N6O6

Formula Wt.

650.60

IUPAC Name

(Z)-but-2-enedioic acid;8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-piperazin-1-yl-3-(trifluoromethyl)phenyl]imidazo[4,5-c]quinolin-2-one

Synonym

BGT226

Solubility

DMSO 30 mg/mL (46.11 mM) Water Insoluble Ethanol Insoluble

Appearance

Off-white Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

N8604 MSDS PDF

Info Sheet

N8604 Info Sheet PDF

References

Phan TN, Baek KH, Lee N, et al. In vitro and in vivo activity of mTOR kinase and PI3K inhibitors against Leishmania donovani and Trypanosoma brucei. Molecules. 2020 Apr 23;25(8):1980. PMID: 32340370.

Hassett M, Sternberg A, Roepe P. Inhibition of human class I vs class III phosphatidylinositol 3’-kinases. Biochemistry. 2017 Aug 22;56(33):4326-4334. PMID: 28719179.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A4000

    AK-1

    SIRT2 inhibitor.

    ≥99%
  • T8269

    (S)-ar-Turmerone

    Sesquiterpene found in Curcuma.

    ≥97%
  • G0175

    Gastric Inhibitory Peptide, human

    Endogenous peptide hormone, somatostatin analog...

    ≥95%
  • P698574

    Prolylrapamycin

    Rapamycin analog

  • V0269

    Vardenafil Dihydrochloride

    PDE5 inhibitor.

    ≥99%
  • T3035

    Thienylheptyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥95%
  • D183745

    Destruxin B

    Cyclic depsipeptide is a secondary metabolite i...

    ≥96%
  • A5033

    4-Aminosalicylic Acid

    Dihydrofolate reductase inhibitor.

    ≥98%
  • D582705

    Dorsomorphin Dihydrochloride

    Inhibitor of ALK2, ALK3, ALK6, and AMPK.

    ≥98%
  • S0032

    Saikosaponin B1

    Saponin found in Bupleurum, Heteromorpha, and S...

    ≥98%
  • C0262

    L-Carnitine

    Endogenous quaternary ammonium, required for fa...

    ≥98%
  • F4781

    Fludarabine

    Nucleoside (adenosine) analog; DNA chain termin...

    ≥98%
  • S881011

    Swainsonine

    Antineoplastic immunomodulator.

    ≥98%
  • T174441

    Telacebec

    Anti-tuberculosis

    ≥98%
  • D3208

    Diclazuril

    Coccidiostat, GAPDH inhibitor.

    ≥98%
  • C4535

    Clinafloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • P8167

    Puromycin Aminonucleoside

    Purine nucleoside analog; DNA chain terminator,...

    ≥98%
  • P7057

    Protodioscin

    Saponin found in Dioscorea; Na+/K+ ATPase and C...

    ≥98%
  • D017538

    Danoprevir

    May be useful against COVID-19

    ≥98%
  • A7204

    AS-605240

    p110δ PI3K inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only