Pantoprazole Sodium Sesquihydrate

Name: Pantoprazole Sodium Sesquihydrate
SKU: P0256
Availability: InStock

Product ID P0256

Cas No. 164579-32-2

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Pantoprazole is an H+/K+ ATPase inhibitor that exhibits antacid, anti-parasitic, and anticancer chemotherapeutic activities. Pantoprazole is clinically used to treat gastroesophageal reflux disease (GERD), although its inhibition of ROCK-2 causes a decrease in gastroesophageal sphincter muscle tone. In Trichomonas, pantoprazole inhibits uridine nucleoside ribohydrolase activity. Additionally, pantoprazole increases tumor-associated macrophage recruitment in the tumor microenvironment, inhibiting tumor growth in vivo.

Product Info

Cas No.	164579-32-2
Purity	≥98%
Formula	C₁₆H₁₄F₂N₃NaO₄S • 3/2 H₂O
Formula Wt.	432.37
Chemical Name	5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)- methyl]sulfinyl]-1H-benzimidazole sodium salt
IUPAC Name	sodium;5-(difluoromethoxy)-2-[(3, 4-dimethoxypyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
Synonym	Eupantol, Pantozol, Protonix, Somac
Melting Point	>30°C (dec)
Solubility	Soluble in water or ethanol.
Appearance	Almost white or white crystalline powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	P0256 MSDS PDF
Info Sheet	P0256 Info Sheet PDF

References

Welsh C, Kasirer MY, Pan J, et al. Pantoprazole decreases gastroesophageal muscle tone in newborn rats via rho-kinase inhibition. Am J Physiol Gastrointest Liver Physiol. 2014 Apr 3. [Epub ahead of print]. PMID: 24699328.

Shea TA, Burburan PJ, Matubia VN, et al. Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1080-4. PMID: 24468412.

Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Vishvakarma NK, Singh SM. Immunopotentiating effect of proton pump inhibitor pantoprazole in a lymphoma-bearing murine host: Implication in antitumor activation of tumor-associated macrophages. Immunol Lett. 2010 Nov 30;134(1):83-92. PMID: 20837061.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Comments
This field is for validation purposes and should be left unchanged.

Pantoprazole Sodium Sesquihydrate

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Ifosfamide

Sulfamethoxazole

Bradykinin (2-9)

Natamycin

Bleomycin A5 Hydrochloride Cu

2-n-Butylthiophene

AM630

Asparaginase

TL-32711

3-Methyladenine

Indole-3-carbinol

Secretin Acetate

Docosahexaenoic Acid (all cis-4,7,10,13,16,19) Methyl Ester

Procarbazine Hydrochloride

Myelin Oligodendrocyte Glycoprotein (35-55), rat

10-Deacetyltaxol B

Xylosyltaxol

Calcitonin, human

α-Cembrenediol

Evodiamine

Footer