LKT Labs

Biochemicals for Life Science Research

Prolactin-Releasing Peptide (1-31), human

Prolactin-Releasing Peptide (1-31), human

Product ID P6850
Cas No.
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $735.90 Please Inquire
Bulk Quote

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Description

Prolactin-releasing peptide (PrP) is an endogenous peptide hormone that binds GPR10 receptors and stimulates leutinizing hormone-releasing hormone (LHRH) release, causing secretion of leutinizing hormone (LH) and follicle-stimulating hormone (FSH) in the hypothalamus. PrP also induces prolactin release in female animals. PrP secretion is increased by food intake and it forms a negative feedback loop by exhibiting anorexigenic activity, decreasing food intake in an oxytocin-dependent manner. PrP exhibits some immunostimulatory and potentially pro-inflammatory activities, increasing expression of pro-inflammatory cytokines and ROS in leukocytes.

Product Info

Purity

≥98%
Formula

C160H252N56O42S
Formula Wt.

3664.2
Synonym

PrRP-31
Solubility

Soluble in water (2 mg/mL).

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

P6850 MSDS PDF
Info Sheet

P6850 Info Sheet PDF

References

Yamashita M, Takayanagi Y, Yoshida M, et al. Involvement of prolactin-releasing peptide in the activation of oxytocin neurones in response to food intake. J Neuroendocrinol. 2013 May;25(5):455-65. PMID: 23363338.

Romero A, Manríquez R, Alvarez C, et al. Prolactin-releasing peptide is a potent mediator of the innate immune response in leukocytes from Salmo salar. Vet Immunol Immunopathol. 2012 Jun 30;147(3-4):170-9. PMID: 22578983.

Seal LJ, Small CJ, Kim MS, et al. Prolactin releasing peptide (PrRP) stimulates luteinizing hormone (LH) and follicle stimulating hormone (FSH) via a hypothalamic mechanism in male rats. Endocrinology. 2000 May;141(5):1909-12. PMID: 10803604.

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