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(R)-P7C3-OMe

(R)-P7C3-OMe

Product ID P0110
Cas No. 1235481-43-2
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $117.70 In stock
25 mg $390.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

This compound is a methoxy derivative of parent compound P7C3, an aminopropyl carbazole that exhibits antidepressant and neuroprotective activities. In animal models of chronic social defeat stress, P7C3 increases survival of dentate gyrus neurons. P7C3 also inhibits MPTP-induced neuronal death in animal models of Parkinson’s disease and delays the onset and preserves motor function in animal models of amyotrophic lateral sclerosis (ALS).

Product Info

Cas No.

1235481-43-2

Purity

≥98%

Formula

C22H20Br2N2O2

Formula Wt.

504.21

Synonym

O-methoxy-P7C3, P7C3-OMe

Solubility

DMSO: ≥ 33 mg/mL

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

P0110 MSDS PDF

Info Sheet

P0110 Info Sheet PDF

References

Walker AK, Rivera PD, Wang Q, et al. The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis. Mol Psychiatry. 2014 Apr 22. [Epub ahead of print]. PMID: 24751964.

De Jesús-Cortés H, Xu P, Drawbridge J, et al. Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17010-5. PMID: 23027934.

Tesla R, Wolf HP, Xu P, et al. Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17016-21. PMID: 23027932.

Custom Order

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