Description
Rolipram is known to be an antidepressant and anxiolytic-like agent that has been found to stimulate angiogenesis and attentuate neuronal apoptosis in ischemic rats.
Product Unit Size | Cost | Quantity | Stock |
---|
Rolipram is known to be an antidepressant and anxiolytic-like agent that has been found to stimulate angiogenesis and attentuate neuronal apoptosis in ischemic rats.
Cas No. | 61413-54-5 |
---|---|
Purity | ≥98% |
Formula | C16H21NO3 |
Formula Wt. | 275.35 |
Chemical Name | 4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one |
IUPAC Name | 4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone |
Synonym | ZK62711, Rolipramum |
Melting Point | 128-129°C |
Solubility | Soluble in DMSO (warm 25mg/ml), ethanol (25 mg/ml warm). |
Appearance | White to off-white powder |
Store Temp | Ambient |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Hu S, Cao Q, Xu P, et al. Rolipram stimulates angiogensis and attenuates neuronal apoptosis through the cAMP/cAMP-responsive element binding protein pathway following ischemic stroke in rats. Exp Ther Med. 2016 Mar; 11(3):1005-1010. PMID: 26998028.
Li YF, Huang Y, Amsdell S, et al. Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 inhibitor rolipram on behavior depend on cyclic AMP response element binding protein-mediated neurogenesis in the hippocampus. Neuropsychopharmacology. 2009 Oct; 34(11):2404-2419. PMID: 19516250.
Pt-based DNA cross-linker.
Organosulfur found in garlic.
Found in the propolis of honey bees.
Selective inhibitor of LRRK2.
Selective inhibitor of cytochrome P450 1B1 (CYP...
Monoterpene found in various plant sources.
Synephrine is an endogenous alkaloid.
Tamoxifen analog; SERM.
Proteasome inhibitor.
Islet β cell proliferation stimulator.
NDRI inhibitor
Iron chelator.
Snake venom found in Bothrops alternatus urutu....
FGFR inhibitor.
PI3K and mTOR inhibitor.
Saponin found in Bupleurum, Heteromorpha, and S...
Steroid; glucocorticoid agonist.
Caspase 9 substrate.
PDK1 inhibitor.
BACE1 inhibitor