• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
SB-202190

SB-202190

Product ID S041001
Cas No. 152121-30-7
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $68.30 In stock
25 mg $173.30 In stock
100 mg $519.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

SB-202190 is a highly selective p38 MAPK inhibitor. In a rabbit model, treatment with SB-202190 after filtering glaucoma surgery improved bleb characteristics and intraocular pressure. In a chronic hypoperfusion rat model of vascular dementia, treatment with SB-202190 reduced apoptosis of hippocampal neurons and rescued spatial learning and memory deficits.

Product Info

Cas No.

152121-30-7

Purity

≥99%

Formula

C20H14FN3O

Formula Wt.

331.35

Chemical Name

4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol

IUPAC Name

4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-dihydroimidazol-2-ylidene]cyclohexa-2,5-dien-1-one

Synonym

SB202190; SB 202190; FHPI; UNII-PVX798P8GI ; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole

Solubility

Soluble in DMSO to 100 mM, 20mg/mL in ethanol, 2mg/mL in Ethyl acetate

Appearance

Yellow Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

S041001 MSDS PDF

Info Sheet

S041001 Info Sheet PDF

References

Nassar K, Tura A, Luke J, et al. A p38 MAPK inhibitor improves outcome after glaucoma filtration surgery. J Glaucoma. 2015 Feb;24(2):165-178. PMID: 25493622.

Yang S, Zhou G, Liu H, et al. Protective effects of p38 MAPK inhibitor SB202190 against hippocampal apoptosis and spatial learning and memory deficits in a rat model of vascular dementia. Biomed Red Int. 2013;2013:215798. PMID: 24455679.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A600002

    AP-26113

    Pan inhibitor of ALK.

    ≥98%
  • D6958

    Droloxifene Citrate

    Tamoxifen analog; SERM.

    ≥98%
  • C0365

    Carvedilol

    FIASMA; α1- and β1/2-adrenergic antagonist.

    ≥98%
  • H1992

    Hexaconazole

    Triazole; demethylation inhibitor.

    ≥95%
  • K740640

    KSQ-4279

    USP1 inhibitor

    ≥98%
  • R183731

    Resiquimod

    Toll-like receptor 7/8 agonist

    ≥98%
  • C0367

    S-(−)-Carbidopa Monohydrate

    Hydrazine; L-amino acid decarboxylase inhibitor...

    ≥98%
  • A0099

    A-779

    Mas antagonist.

    ≥95%
  • O9458

    Oxolinic Acid

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥98%
  • A7672

    Atropine Sulfate Monohydrate

    Tropane alkaloid found in Solanaceae plants; mA...

    ≥98%
  • T7056

    Troglitazone

    Thiazolidinedione; PPARγ agonist, ATP-sensitiv...

    ≥97%
  • R1776

    Resveratrol

    Phenolic phytoalexin found in soy, grapes, and ...

    ≥99%
  • B1769

    Bergenin

    Trihydroxybenzoic acid glycoside found in Berge...

    ≥98%
  • V1745

    Veliparib

    PARP inhibitor.

    ≥99%
  • H9861

    Hypericin

    Naphthodianthrone found in Hypericum; dopamine ...

    ≥98%
  • I0010

    5-(9-Isopropyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine

    Intermediate in the synthesis of purine analogs...

    ≥98%
  • D5794

    Doxorubicin Hydrochloride

    Anthracycline, DNA intercalator; topoisomerase ...

    ≥98%
  • C0247

    Calcineurin Autoinhibitory Peptide

    Peptide; calcineurin inhibitor.

    ≥95%
  • K1776

    Ketotifen Fumarate

    H1 histamine and LT antagonist, PDE inhibitor.<...

    ≥98%
  • M174446

    Meleagrin

    FabI inhibitor

    ≥99%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only