• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
SU-5402

SU-5402

Product ID S801001
Cas No. 215543-92-3
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $102.30 In stock
25 mg $333.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

SU-5402 is an inhibitor of vascular endothelial growth factor receptor 2 (VEGFR-2), platelet-derived growth factor receptor (PDGFR), and fibroblast growth factor receptor (FGFR). In multiple myeloma, SU5402 worked with PD173074 to supress tumor growth via FGFR3 inhibition. SU5402 was used to examine the role of FGFR during neural crest differentiation, where its inhibition promoted human pluripotent stem cells to commit to a neural crest cell fate.

Product Info

Cas No.

215543-92-3

Purity

≥98%

Formula

C17H16N2O3

Formula Wt.

296.33

IUPAC Name

3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid

Synonym

SU5402; 3-[3-(2-Carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

S801001 MSDS PDF

Info Sheet

S801001 Info Sheet PDF

References

Sun L., Tran N., et al. Design, synthesis, and evaluations of substituted 3-[(3- or 4-carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as inhibitors of VEGF, FGF, and PDGF receptor tyrosine kinases. J Med Chem. 42(25):5120-30 (1999). PMID: 10602697.

Grand E., Chase A., et al. Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074. Leukemia. 18(5):962-6 (2004). PMID: 15029211.

Jaroonwitchawan T., Muangchan P., et al. Inhibition of FGF signaling accelerates neural crest cell differentiation of human pluripotent stem cells. Biochem Biophys Res Commun. 481(1-2):176-181 (2016). PMID: 27816457.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • H5748

    D,L-Homocysteine Thiolactone Hydrochloride

    Heterocyclic derivative of cysteine, alters pro...

    ≥99%
  • M1708

    Mecamylamine Hydrochloride

    Monoterpene; nAChR antagonist.

    ≥98%
  • G1651

    Geniposidic Acid

    Iridoid glucoside found in Eucommia, Castilleja...

    ≥98%
  • C5592

    CNX-774

    BTK inhibitor.

    ≥98%
  • I527211

    Infigratinib Phosphate

    FGFR inhibitor.

    ≥98%
  • I7870

    Itraconazole

    Triazole; 14-α demethylase inhibitor, Smo modu...

    ≥98%
  • C5654

    Concanavalin A

    Lectin found in Canavelia, plant mitogen that b...

  • R2812

    Recombinant HIV-1 gp-120

    Recombinant HIV glycoprotein antigen fragment.<...

    ≥95%
  • B8144

    Bulleyaconitine A

    Found in Aconitum bulleyanum; voltage-gated Na+...

    ≥95%
  • A9801

    Azaperone

    Butyrophenone; α-adrenergic, D2, histamine ant...

    ≥98%
  • U698574

    Urolithin A

    Ellagic acid derivative produced by gut microfl...

    ≥98%
  • T1298

    TDZD-8

    GSK-3β inhibitor.

    ≥98%
  • D5662

    Dopamine Hydrochloride

    Endogenous hormone neurotransmitter, involved i...

    ≥99%
  • A9600

    AZD-3463

    ALK and IGF-1R inhibitor.

    ≥99%
  • G8800

    GW-788388

    ALK5 (activin-like) antagonist.

    ≥97%
  • C104762

    CCT-245737

    CHK1 inhibitor.

    ≥98%
  • T3041

    Thienylpropyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥98%
  • C9808

    CZC-54252

    LRRK2 inhibitor.

    ≥98%
  • C3251

    Cinnarizine

    FIASMA, L-type Ca2+ channel blocker, D2 antagon...

    ≥98%
  • C0150

    Camptothecin

    Quinolone alkaloid precursor of irinotecan, ori...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only