• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
[Tyr4]-Bombesin

[Tyr4]-Bombesin

Product ID B5649
Cas No.
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $81.70 Please Inquire
2 mg $138.90 Please Inquire
5 mg $245.30 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Bombesin is a gastrin-releasing peptide analog that binds bombesin and GRP receptors. Derivatives of bombesin are currently under investigation as cancer imaging tools, as bombesin receptors are often overexpressed in tumor tissues. Bombesin itself exhibits neuromodulatory, hepatoprotective, cardiomodulatory, and vasoconstrictive activities. Bombesin increases the frequency and amplitude of IPSCs in the entorhinal cortex, likely due to Ca2+-mediated increases in GABA release. In animal models of liver disease, bombesin increases proliferation of oval cells and hepatocytes, increases levels of glutathione, and decreases portal endotoxemia. Bombesin also exhibits pressor-like effects, increasing mean arterial pressure, blood pressure, and heart rate.

Product Info

Purity

≥95%

Formula

C74H109N24O19S

Formula Wt.

1670.90

Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

B5649 MSDS PDF

Info Sheet

B5649 Info Sheet PDF

References

Zhang HP, Xiao Z, Cilz NI, et al. Bombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex. Hippocampus. 2014 Jan;24(1):21-31. PMID: 23966303.

Okarvi SM, Jammaz IA. Preparation and evaluation of bombesin peptide derivatives as potential tumor imaging agents: effects of structure and composition of amino acid sequence on in vitro and in vivo characteristics. Nucl Med Biol. 2012 Aug;39(6):795-804. PMID: 22381782.

Assimakopoulos SF, Tsamandas AC, Alexandris IH, et al. Stimulation of oval cell and hepatocyte proliferation by exogenous bombesin and neurotensin in partially hepatectomized rats. World J Gastrointest Pathophysiol. 2011 Dec 15;2(6):146-54. PMID: 22180848.

Zogovic B, Pilowsky PM. Intrathecal bombesin is sympathoexcitatory and pressor in rat. Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1486-94. PMID: 21849634.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A985134

    AZD-9291

    EGFR inhibitor.

    ≥99%
  • A5160

    Ampicillin Trihydrate

    β-lactam; transpeptidase inhibitor.

    ≥97%
  • B1996

    BEZ235

    PI3K and mTOR inhibitor.

    ≥98%
  • D0363

    Daptomycin

    Anionic lipopeptide, alters cell membrane organ...

    ≥97%
  • C2950

    Chloroquine Diphosphate

    Aminoquinoline, binds heme, causes cell lysis.<...

    ≥98%
  • A980005

    AZ-5104

    Inhibitor of EGFR.

    ≥98%
  • C1650

    β-Cembrenediol Methyl Ether

    Diterpene found in tobacco plants and cigarette...

    ≥98%
  • N5767

    Norethindrone

    Steroid hormone, contraceptive; PR agonist.

    ≥98%
  • C8502

    CV-70

    1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhi...

    ≥70%
  • S5200

    SNA 1

    Sialic-acid sensing lectin.

    ≥98%
  • I5440

    INK128

    mTOR inhibitor.

    ≥99%
  • C9200

    CX-6258

    Pim kinase inhibitor.

    ≥98%
  • B5874

    Bosutinib

    Src and Abl inhibitor.

    ≥98%
  • S8014

    Substance P, Free Acid

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • C1621

    CEF4

    Peptide, vSrc-induced cytokine.

    ≥95%
  • G4518

    Glucaric Acid Calcium Tetrahydrate

    Oxidized non-cylic hexose sugar.

    ≥98%
  • C0248

    Calcineurin Substrate

    Peptide used to measure in vitro calcineurin ac...

    ≥96%
  • S0072

    5S rRNA modificator

    Electrophile used in 2’-hydroxyl acylation of...

    ≥98%
  • T3134

    Thiostrepton

    Thiazole; proteasome inhibitor, protein translo...

    ≥97%, HPLC
  • S5868

    Sorafenib

    c-Raf, Ret, VEGFR2 inhibitor, potential STAT3/5...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only