LKT Labs

Biochemicals for Life Science Research

Vidarabine Monophosphate

Vidarabine Monophosphate

Product ID V3213
Cas No. 29984-33-6
Purity ≥98.0%
Product Unit SizeCostQuantityStock
10 mg $61.00 In stock
100 mg $123.00 In stock
500 mg $306.00 In stock
1 g $460.00 In stock
Bulk Quote

Quicklinks

Description

Vidarabine is a long-acting antiviral originally found in the marine sponge Tethyra crypta. Vidarabine is an adenosine analog in which the D-ribose constituent is replaced by D-arabinose, preventing formation of phosphodiester bridges upon incorporation into DNA. This compound is a substrate for and inhibitor of viral DNA polymerase and may also inhibit ribonucleotide reductase. Vidarabine is used to treat subjects with severe chronic Epstein-Barr virus, herpes simplex virus, or human papilloma virus, as well as immunocompromised patients with adenovirus-induced hemorrhagic cystitis.

Product Info

Cas No.

29984-33-6
Purity

≥98.0%
Formula

C10H14N5O7P
Formula Wt.

347.22
Chemical Name

9-(5-O-Phosphono-beta-D-arabinofuranosyl)adenine
IUPAC Name

[(2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
Synonym

Ara-AMP
Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

V3213 MSDS PDF
Info Sheet

V3213 Info Sheet PDF

References

Whitley RJ. The use of antiviral drugs during the neonatal period. Clin Perinatol. 2012 Mar;39(1):69-81. PMID: 22341538.

Wilhelmus KR. Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD002898. PMID: 21154352.

Sagar S, Kaur M, Minneman KP. Antiviral lead compounds from marine sponges. Mar Drugs. 2010 Oct 11;8(10):2619-38. PMID: 21116410.

Kurosaki K, Miwa N, Yoshida Y, et al. Therapeutic basis of vidarabine on adenovirus-induced haemorrhagic cystitis. Antivir Chem Chemother. 2004 Sep;15(5):281-5. PMID: 15535050.

Niwa K, Tagami K, Lian Z, et al. Topical vidarabine or 5-fluorouracil treatment against persistent HPV in genital (pre)cancerous lesions. Oncol Rep. 2003 Sep-Oct;10(5):1437-41. PMID: 12883720.

Kimura H, Morita M, Tsuge I, et al. Vidarabine therapy for severe chronic active Epstein-Barr virus infection. J Pediatr Hematol Oncol. 2001 Jun-Jul;23(5):294-9. PMID: 11464986.

Nimit Y, Law J, Daly JW. Binding of 2',5'-dideoxyadenosine to brain membranes. Comparison to P-site inhibition of adenylate cyclase. Biochem Pharmacol. 1982 Oct 15;31(20):3279-87. PMID: 6983353.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C4517

    Clenbuterol Hydrochloride

    β2-adrenergic agonist.

    ≥98%
  • V182705

    Verubecestat

    BACE1 inhibitor

    ≥98%
  • C0368

    Carveol

    Terpene alcohol found in spearmint oil; TRPV3 a...

    ≥99%
  • H9614

    Hydrochlorothiazide

    Thiazide diuretic; NCCT inhibitor, carbonic anh...

    ≥98%
  • F1650

    Fenbendazole

    Benzimidazole; microtubule polymerization inhib...

    ≥98%
  • B4517

    Bleomycin A5 Hydrochloride

    Glycopeptide, induces DNA strand breaks.

    ≥90%
  • T2834

    Thiolutin

    Dithiolopyrrolone; RNA polymerase inhibitor.

    ≥98%
  • F4782

    Fludarabine Phosphate

    Nucleoside (adenosine) analog; DNA chain termin...

    ≥98%
  • S8110

    Sucralfate

    Antacid; pepsin inhibitor. Assay (Polysaccharid...

    Assay (Polysaccharide sulfate) 30-38%
  • I0518

    I-BET-762

    BRD inhibitor.

    ≥98%
  • C9882

    Cytochalasin E

    Mycotoxin produced by Aspergillus; actin polyme...

    ≥98%
  • L0349

    Lamotrigine

    R-type Ca2+ and voltage-gated Na+ channel block...

    ≥98%
  • N2400

    NG-52

    Purine, purvalenol A analog; CDK2, Cdc28p, Pho8...

    ≥98%
  • C5592

    CNX-774

    BTK inhibitor.

    ≥98%
  • T0298

    Tazobactam

    β-lactamase inhibitor.

    ≥98%
  • B8363

    Bupropion Hydrochloride

    α3β2, α3β4, α4β2 nAChR antagonist, indire...

    ≥98%
  • R3310

    Ricobendazole

    Nitroimidazole; microtubule polymerization inhi...

    ≥98%
  • T3324

    Tigecycline

    Glycylcycline; protein synthesis inhibitor.

    ≥98%
  • P8117

    Puerarin, High Purity

    Isoflavone found in Pueraria; 5-HT2C and GABA-A...

    ≥99%
  • P7021

    Prednisone Acetate

    Synthetic prednisolone prodrug; glucocorticoid ...

    ≥98%