LKT Labs

Biochemicals for Life Science Research

Vidarabine Monophosphate

Vidarabine Monophosphate

Product ID V3213
Cas No. 29984-33-6
Purity ≥98.0%
Product Unit SizeCostQuantityStock
10 mg $61.40 In stock
100 mg $122.70 In stock
500 mg $306.20 In stock
1 g $459.60 In stock
Bulk Quote

Quicklinks

Description

Vidarabine is a long-acting antiviral originally found in the marine sponge Tethyra crypta. Vidarabine is an adenosine analog in which the D-ribose constituent is replaced by D-arabinose, preventing formation of phosphodiester bridges upon incorporation into DNA. This compound is a substrate for and inhibitor of viral DNA polymerase and may also inhibit ribonucleotide reductase. Vidarabine is used to treat subjects with severe chronic Epstein-Barr virus, herpes simplex virus, or human papilloma virus, as well as immunocompromised patients with adenovirus-induced hemorrhagic cystitis.

Product Info

Cas No.

29984-33-6
Purity

≥98.0%
Formula

C10H14N5O7P
Formula Wt.

347.22
Chemical Name

9-(5-O-Phosphono-beta-D-arabinofuranosyl)adenine
IUPAC Name

[(2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
Synonym

Ara-AMP
Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

V3213 MSDS PDF
Info Sheet

V3213 Info Sheet PDF

References

Whitley RJ. The use of antiviral drugs during the neonatal period. Clin Perinatol. 2012 Mar;39(1):69-81. PMID: 22341538.

Wilhelmus KR. Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD002898. PMID: 21154352.

Sagar S, Kaur M, Minneman KP. Antiviral lead compounds from marine sponges. Mar Drugs. 2010 Oct 11;8(10):2619-38. PMID: 21116410.

Kurosaki K, Miwa N, Yoshida Y, et al. Therapeutic basis of vidarabine on adenovirus-induced haemorrhagic cystitis. Antivir Chem Chemother. 2004 Sep;15(5):281-5. PMID: 15535050.

Niwa K, Tagami K, Lian Z, et al. Topical vidarabine or 5-fluorouracil treatment against persistent HPV in genital (pre)cancerous lesions. Oncol Rep. 2003 Sep-Oct;10(5):1437-41. PMID: 12883720.

Kimura H, Morita M, Tsuge I, et al. Vidarabine therapy for severe chronic active Epstein-Barr virus infection. J Pediatr Hematol Oncol. 2001 Jun-Jul;23(5):294-9. PMID: 11464986.

Nimit Y, Law J, Daly JW. Binding of 2',5'-dideoxyadenosine to brain membranes. Comparison to P-site inhibition of adenylate cyclase. Biochem Pharmacol. 1982 Oct 15;31(20):3279-87. PMID: 6983353.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • N3225

    Nigericin Sodium

    Polyether cationic ionophore.

    ≥98%
  • C104761

    CCT-196969

    pan-Raf inhibitor.

    ≥98%
  • L3454

    Lincomycin Hydrochloride Monohydrate

    Lincosamide; peptidyl transferase inhibitor, pr...

    ≥98%
  • B1874

    Bestatin Hydrochloride

    Dipeptide; aminopeptidase (N/CD13) inhibitor.

    ≥98%
  • D3304

    Dibenzoylmethane, 98%

    Aromatic 1,3-diketone acetylacetone derivative ...

    ≥98%
  • P982691

    Pyridostatin Trifluoroacetate Salt

    G-quadruplex ligand; DNA breakage inducer.

    ≥95%
  • O4531

    Oligomycin A

    Macrolide; F1F0 ATP synthase inhibitor.

    ≥97%, TLC, HPLC
  • T6932

    Triflumizole

    Imidazole; PPARγ agonist, RORγ inverse agonis...

    ≥95%
  • I761004

    Itaconic Acid

    Polymer precursor

    ≥99%
  • J889280

    JWH 015

    Cannabinoid receptor 2 selective agonist.

    ≥98%
  • S8251

    Sulfluramid

    Perfluorinated insecticide.

    ≥95%
  • T1030

    N-Des-2-methylpropan-2-ol Docetaxel

    N-Des-2-methylpropan-2-ol Docetaxel is an impur...

    ≥90%
  • D3210

    Diclofenac free acid

    Somewhat selective in inhibiting COX-2 over COX...

    ≥99%
  • T0090

    7-(Triethylsilyl)-baccatin III

    Synthetic taxol synthesis intermediate; microtu...

    ≥98%
  • P9671

    Pyrazinamide

    Nicotinamide analog prodrug; fatty acid synthet...

    ≥98%
  • I7359

    1-Isothiocyanato-8-(methylsulfenyl)-octane

    ITC, erucin analog.

    ≥98%
  • A7309

    Ascorbyl Palmitate

    Fat-soluble vitamin C derivative.

    ≥95%
  • M400220

    MK-2206 Dihydrochloride

    Akt inhibitor.

    ≥99%
  • P0218

    Paeoniflorin

    Found in Paeonia; L-type Ca2+ channel blocker.<...

    ≥98%
  • T2404

    TG101348

    JAK2 inhibitor.

    ≥98%