LKT Labs

Biochemicals for Life Science Research

Vidarabine Monophosphate

Vidarabine Monophosphate

Product ID V3213
Cas No. 29984-33-6
Purity ≥98.0%
Product Unit SizeCostQuantityStock
10 mg $61.00 In stock
100 mg $123.00 In stock
500 mg $306.00 In stock
1 g $460.00 In stock
Bulk Quote

Quicklinks

Description

Vidarabine is a long-acting antiviral originally found in the marine sponge Tethyra crypta. Vidarabine is an adenosine analog in which the D-ribose constituent is replaced by D-arabinose, preventing formation of phosphodiester bridges upon incorporation into DNA. This compound is a substrate for and inhibitor of viral DNA polymerase and may also inhibit ribonucleotide reductase. Vidarabine is used to treat subjects with severe chronic Epstein-Barr virus, herpes simplex virus, or human papilloma virus, as well as immunocompromised patients with adenovirus-induced hemorrhagic cystitis.

Product Info

Cas No.

29984-33-6
Purity

≥98.0%
Formula

C10H14N5O7P
Formula Wt.

347.22
Chemical Name

9-(5-O-Phosphono-beta-D-arabinofuranosyl)adenine
IUPAC Name

[(2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
Synonym

Ara-AMP
Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

V3213 MSDS PDF
Info Sheet

V3213 Info Sheet PDF

References

Whitley RJ. The use of antiviral drugs during the neonatal period. Clin Perinatol. 2012 Mar;39(1):69-81. PMID: 22341538.

Wilhelmus KR. Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD002898. PMID: 21154352.

Sagar S, Kaur M, Minneman KP. Antiviral lead compounds from marine sponges. Mar Drugs. 2010 Oct 11;8(10):2619-38. PMID: 21116410.

Kurosaki K, Miwa N, Yoshida Y, et al. Therapeutic basis of vidarabine on adenovirus-induced haemorrhagic cystitis. Antivir Chem Chemother. 2004 Sep;15(5):281-5. PMID: 15535050.

Niwa K, Tagami K, Lian Z, et al. Topical vidarabine or 5-fluorouracil treatment against persistent HPV in genital (pre)cancerous lesions. Oncol Rep. 2003 Sep-Oct;10(5):1437-41. PMID: 12883720.

Kimura H, Morita M, Tsuge I, et al. Vidarabine therapy for severe chronic active Epstein-Barr virus infection. J Pediatr Hematol Oncol. 2001 Jun-Jul;23(5):294-9. PMID: 11464986.

Nimit Y, Law J, Daly JW. Binding of 2',5'-dideoxyadenosine to brain membranes. Comparison to P-site inhibition of adenylate cyclase. Biochem Pharmacol. 1982 Oct 15;31(20):3279-87. PMID: 6983353.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • R1780

    trans-Retinoic Acid

    Vitamin A carboxylic acid; RAR agonist.

    ≥98%
  • L960010

    LY-3200882

    TGF-β1 inhibitor.

    ≥98%
  • P2012

    PF-04217903

    Triazolopyrazine; c-MET inhibitor.

    ≥98%
  • D1643

    Delta Sleep Inducing Peptide

    Peptide; GABA potentiator, NMDA negative allost...

    ≥95%
  • R4132

    RKI-1447

    ROCK1/2 inhibitor.

    ≥98%
  • W5727

    Wogonoside

    Flavonoid glycoside found in Scutellaria.

    ≥98%
  • T0117

    Benzyl Analog of Taxol

    Benzyl taxol analog; potential microtubule depo...

    ≥95%
  • V0274

    [Lys8]-Vasopressin

    Peptide, vasopressin analog; V1/2 agonist.

    ≥95%
  • D1770

    Dermorphin Analog

    Synthetic peptide; dermorphin analog; δOR and ...

    ≥95%
  • H0001

    H7

    PKC and PKG inhibitor.

    ≥98%
  • X4402

    XL-147

    Dual inhibitor of PI3K and mTOR.

    ≥98%
  • L0249

    Laminin Peptide YIGSR-NH2

    Laminin-derived peptapeptide.

    ≥98%
  • B030966

    BAY 11-7082

    inhibits inflammatory signaling

    ≥98%
  • C1624

    Cefuroxime Sodium

    β-lactam; penicillin binding protein inhibitor...

    ≥98%
  • I7757

    Itopride Hydrochloride

    AChE inhibitor, D2 antagonist.

    ≥98%
  • P6857

    Protocatechuic Acid

    Polyphenol found in many plants and foods.

    ≥97%
  • C9778

    Cytarabine

    Pyrimidine nucleoside (cytidine) analog; DNA ch...

    ≥98%
  • T0097

    10-Deacetyltaxol B

    Diterpene found in Taxus; potential microtubule...

    ≥98%
  • P5845

    Polydatin

    Stilbenoid glucoside found in Polygonum.

    ≥97%
  • C0274

    Caspofungin Diacetate

    Lipopeptide; 1,3-β-Glucan synthase inhibitor.<...

    ≥95%