Description
2’-Acetyltaxol is an intermediate in taxane synthesis that appears to have minimal effects on microtubule polymerization, although current research is limited.
Product Unit Size | Cost | Quantity | Stock |
---|
2’-Acetyltaxol is an intermediate in taxane synthesis that appears to have minimal effects on microtubule polymerization, although current research is limited.
Cas No. | 92950-40-8 |
---|---|
Purity | ≥98% |
Formula | C49H53NO15 |
Formula Wt. | 895.95 |
Chemical Name | Benzenepropanoic acid, α-(acetyloxy)-β- (benzoyl- amino)-,6,12b-bis(acetyloxy)-12-(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11- dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR) |
IUPAC Name | [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-2-acetyloxy-3-benzamido-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
Synonym | Taxol 2'-acetate, 2’-acetyl taxol |
Appearance | White Crystal Powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Williams HJ, Moyna G, Scott AI, et al. NMR and molecular modeling study of the conformations of taxol 2'-acetate in chloroform and aqueous dimethyl sulfoxide solutions. J Med Chem. 1996 Mar 29;39(7):1555-9. PMID: 8691488.
Mellado W, Magri NF, Kingston DG, et al. Preparation and biological activity of taxol acetates. Biochem Biophys Res Commun. 1984 Oct 30;124(2):329-36. PMID: 6548627.
BRD inhibitor.
Serine protease substrate/inhibitor.
PKC and S6 kinase substrate.
Antihistamine with potential neuroprotective ac...
Loop diuretic; NKCC symporter and KCC2 co-trans...
Diterpene found in brewed, unfiltered coffee; F...
Curcumin derivative.
Organosulfur found in garlic, binds DNA; inward...
ITC precursor found in cruciferous vegetables.<...
PARP inhibitor.
Antioxidant; Nrf2 activator.
Imidazole; 14-α demethylase inhibitor, potenti...
Peptide found in crustaceans; PKA activator.
Isoleucyl-tRNA synthase inhibitor, osteoclast p...
Microtubule polymerization inhibitor.
Triterpenoid
Nitrosourea, DNA cross-linker.
Synthetic peptice; μOR agonist.
Diterpene found in Taxus; potential microtubule...
Vinca alkaloid found in Catharanthus; microtubu...