• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
15-Acetyl-deoxynivalenol

15-Acetyl-deoxynivalenol

Product ID D1761
Cas No. 88337-96-6
Purity ≥98%, TLC
Product Unit SizeCostQuantityStock
0.1 mg $57.20 In stock
1 mg $387.60 In stock
5 mg $1,534.40 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

15-acetyl deoxynivalenol (15-A-DON) a type A trichothecene mycotoxin initially produced by species of Fusarium. 15-A-DON is typically found in grains used for livestock feed as well as human consumption, such as cereal and bread. This compound exhibits potential anticancer and immunomodulatory benefit in vitro, upregulating IL-8 production and inducing apoptosis in Jurkat T cells. 15-A-DON also displays biphasic effects on cytokine production in CD4+ T cells, initially decreasing expression of IL-2, IL-4, and IL-5, then increasing expression of all three after 7 days of exposure.

Product Info

Cas No.

88337-96-6

Purity

≥98%, TLC

Formula

C17H22O7

Formula Wt.

338.35

Chemical Name

[(1R,2R,3S,7R,9R,10R,12S)-3,10-dihydroxy-1,5-dimethyl-4-oxospiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-2-yl]methyl acetate

IUPAC Name

[(1R,2R,3S,7R,9R,10R,12S)-3,10-dihydroxy-1,5-dimethyl-4-oxospiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-2-yl]methyl acetate

Synonym

15-Acetyldeoxynivalenol, 15-A-DON, 15-Acetyl Vomitoxin, 15-AcDON, Deoxynivalenol 15-acetate, DON 15-acetate

Melting Point

185-187°C

Solubility

Soluble in acetonitrile, methanol and ethyl acetate, only slightly soluble in water.

Appearance

White crystalline solid

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

D1761 MSDS PDF

Info Sheet

D1761 Info Sheet PDF

References

Puri KD, Zhong S. The 3ADON population of Fusarium graminearum found in North Dakota is more aggressive and produces a higher level of DON than the prevalent 15ADON population in spring wheat. Phytopathology. 2010 Oct;100(10):1007-14. PMID: 20839936.

Monbaliu S, Van Poucke C, Detavernier C, et al. Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method. J Agric Food Chem. 2010 Jan 13;58(1):66-71. PMID: 19994896.

Gottschalk C, Barthel J, Engelhardt G, et al. Occurrence of type A trichothecenes in conventionally and organically produced oats and oat products. Mol Nutr Food Res. 2007 Dec;51(12):1547-53. PMID: 18030660.

Pestka JJ, Uzarski RL, Islam Z. Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes. Toxicology. 2005 Jan 15;206(2):207-19. PMID: 15588914.

Ouyang YL, Azcona-Olivera JI, Pestka JJ. Effects of trichothecene structure on cytokine secretion and gene expression in murine CD4+ T-cells. Toxicology. 1995 Dec 15;104(1-3):187-202. PMID: 8560498.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F5668

    Forskolin

    Labdane diterpene found in Coleus; PP2A and ade...

    ≥98%
  • G6817

    Green Tea Polyphenols

    Extract containing catechins and flavonoids fou...

    ≥98%
  • M1769

    Meropenem Trihydrate

    β-lactam carbapenem; penicillin binding protei...

    ≥98%
  • K7600

    KT5720

    PKA and PDK1 inhibitor, HCN channel blocker, po...

    ≥98%
  • P9768

    Pyronaridine Tetraphosphate

    Hemantin inhibitor.

    ≥98%
  • E7433

    Etidronate Disodium

    Bisphosphonate, chelating agent.

    ≥98%
  • G1646

    Geldanamycin

    HSP90 inhibitor.

    ≥97%
  • D0004

    Dabrafenib

    B-Raf and c-Raf inhibitor.

    ≥98%
  • A4675

    Alternariol

    Mycotoxin produced by Alternaria; topoisomerase...

    ≥98%
  • A4497

    Alyssin Sulfone

    Naturally sourced ITC, sulfonyl analog of sulfo...

    ≥97%
  • C0365

    Carvedilol

    FIASMA; α1- and β1/2-adrenergic antagonist.

    ≥98%
  • A0102

    A23187 Ca-Mg

    Ca2+ ionophore.

    ≥98%, TLC
  • G733404

    GSK3685032

    Reversible DNMT1-selective inhibitor

    ≥98%
  • F4781

    Fludarabine

    Nucleoside (adenosine) analog; DNA chain termin...

    ≥98%
  • V5725

    Voglibose

    α-glucosidase inhibitor, potential GLP-1 agoni...

    ≥99%
  • T8269

    (S)-ar-Turmerone

    Sesquiterpene found in Curcuma.

    ≥97%
  • A761003

    AT-7519 Hydrochloride

    ATP competitive CDK inhibitor.

    ≥98%
  • L960006

    LY-2606368

    CHK1 inhibitor.

    ≥98%
  • P004080

    PAC-1

    Zinc chelator

    ≥98%
  • C9876

    CYT-387

    JAK2 inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only