15-Acetyl-deoxynivalenol

Name: 15-Acetyl-deoxynivalenol
SKU: D1761
Availability: InStock

Product ID D1761

Cas No. 88337-96-6

Purity ≥98%, TLC

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

15-acetyl deoxynivalenol (15-A-DON) a type A trichothecene mycotoxin initially produced by species of Fusarium. 15-A-DON is typically found in grains used for livestock feed as well as human consumption, such as cereal and bread. This compound exhibits potential anticancer and immunomodulatory benefit in vitro, upregulating IL-8 production and inducing apoptosis in Jurkat T cells. 15-A-DON also displays biphasic effects on cytokine production in CD4+ T cells, initially decreasing expression of IL-2, IL-4, and IL-5, then increasing expression of all three after 7 days of exposure.

Product Info

Cas No.	88337-96-6
Purity	≥98%, TLC
Formula	C₁₇H₂₂O₇
Formula Wt.	338.35
Chemical Name	[(1R,2R,3S,7R,9R,10R,12S)-3,10-dihydroxy-1,5-dimethyl-4-oxospiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-2-yl]methyl acetate
IUPAC Name	[(1R,2R,3S,7R,9R,10R,12S)-3,10-dihydroxy-1,5-dimethyl-4-oxospiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-2-yl]methyl acetate
Synonym	15-Acetyldeoxynivalenol, 15-A-DON, 15-Acetyl Vomitoxin, 15-AcDON, Deoxynivalenol 15-acetate, DON 15-acetate
Melting Point	185-187°C
Solubility	Soluble in acetonitrile, methanol and ethyl acetate, only slightly soluble in water.
Appearance	White crystalline solid

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	D1761 MSDS PDF
Info Sheet	D1761 Info Sheet PDF

References

Puri KD, Zhong S. The 3ADON population of Fusarium graminearum found in North Dakota is more aggressive and produces a higher level of DON than the prevalent 15ADON population in spring wheat. Phytopathology. 2010 Oct;100(10):1007-14. PMID: 20839936.

Monbaliu S, Van Poucke C, Detavernier C, et al. Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method. J Agric Food Chem. 2010 Jan 13;58(1):66-71. PMID: 19994896.

Gottschalk C, Barthel J, Engelhardt G, et al. Occurrence of type A trichothecenes in conventionally and organically produced oats and oat products. Mol Nutr Food Res. 2007 Dec;51(12):1547-53. PMID: 18030660.

Pestka JJ, Uzarski RL, Islam Z. Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes. Toxicology. 2005 Jan 15;206(2):207-19. PMID: 15588914.

Ouyang YL, Azcona-Olivera JI, Pestka JJ. Effects of trichothecene structure on cytokine secretion and gene expression in murine CD4+ T-cells. Toxicology. 1995 Dec 15;104(1-3):187-202. PMID: 8560498.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Email
This field is for validation purposes and should be left unchanged.

15-Acetyl-deoxynivalenol

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Palmitoyl-L-carnitine

R,S-Sulforaphane, High Purity

Mogroside IV

Bupropion Hydrochloride

AWD 131-138

n-Valeric Acid

Oxytetracycline Hydrochloride

Y-320

Ciprofibrate

YM-155

TMS

Bradykinin (2-9)

SN-011

Lercanidipine Hydrochloride

J-147

AMG-337

Melatonin

Pantoprazole Sodium Sesquihydrate

Dexamethasone Acetate Monohydrate

NVP-AUY922

Footer