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AGI-6780

AGI-6780

Product ID A2532
Cas No. 1432660-47-3
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $90.00 In stock
5 mg $160.00 In stock
25 mg $641.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

AGI-6780 is an inhibitor of isocitrate dehydrogenase (IDH) that displays anticancer activity. This compound induces differentiation in acute myeloid leukemia (AML) and TF-1 erythroleukemia cells.

Product Info

Cas No.

1432660-47-3

Purity

≥98%

Formula

C21H18F3N3O3S2

Formula Wt.

481.51

IUPAC Name

N-Cyclopropyl-4-(3-thienyl)-3-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)benzenesulfonamide

Synonym

AGI 6780, AGI6780

Solubility

DMSO 96 mg/mL (199.37 mM) Ethanol 96 mg/mL (199.37 mM) Water Insoluble

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A2532 MSDS PDF

Info Sheet

A2532 Info Sheet PDF

References

Lee WY, Chen KC, Chen HY, et al. Potential mitochondrial isocitrate dehydrogenase R140Q mutant inhibitor from traditional Chinese medicine against cancers. Biomed Res Int. 2014;2014:364625. PMID: 24995286.

Wang F, Travins J, DeLaBarre B, et al. Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. Science. 2013 May 3;340(6132):622-6. PMID: 23558173.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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