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Bactenecin

Bactenecin

Product ID B0108
Cas No. 116229-36-8
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $180.30 In stock
1 mg $330.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Bactenecin is a cathelicidin-derived antimicrobial peptide (AMP) found in bovine neutrophils. Bactenecin exhibits antibiotic activity, increasing membrane permeability and inhibiting growth. Bactenecin is an effective antibacterial peptide, displaying activity against Burkholderia, Escherichia, Pseudomonas, Salmonella, Staphylococcus, and Enterobacter.

Product Info

Cas No.

116229-36-8

Purity

≥95%

Formula

C63H118N24O13S2

Formula Wt.

1483.90

IUPAC Name

2-[[28-[[2-[[2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-13,22-di(butan-2-yl)-10,25-bis[3-(diaminomethylideneamino)propyl]-6,9,12,15,18,21,24,27-octaoxo-7,16,19-tri(propan-2-yl)-1,2-dithia-5,8,11,14,17,20,23,26-octazacyclononacosane-4-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid

Synonym

Arg-leu-cyclo(cys-arg-ile-val-val-ile-arg-val-cys)-arg, Bac7

Solubility

Soluble in water (1 mg/mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

B0108 MSDS PDF

Info Sheet

B0108 Info Sheet PDF

References

Madhongsa K, Pasan S, Phophetleb O, et al. Antimicrobial action of the cyclic peptide bactenecin on Burkholderia pseudomallei correlates with efficient membrane permeabilization. PLoS Negl Trop Dis. 2013 Jun 13;7(6):e2267. PMID: 23785532.

Lee JY, Yang ST, Lee SK, et al. Salt-resistant homodimeric bactenecin, a cathelicidin-derived antimicrobial peptide. FEBS J. 2008 Aug;275(15):3911-20. PMID: 18616463.

Wu M, Hancock RE. Interaction of the cyclic antimicrobial cationic peptide bactenecin with the outer and cytoplasmic membrane. J Biol Chem. 1999 Jan 1;274(1):29-35. PMID: 9867806.

Custom Order

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