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Benztropine Mesylate

Benztropine Mesylate

Product ID B1955
Cas No. 132-17-2
Purity ≥99%
Product Unit SizeCostQuantityStock
1 g $68.30 In stock
5 g $89.30 In stock
25 g $236.30 In stock
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Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Benztropine is an inhibitor of the dopamine transporter (DAT); it potentiates dopamine overflow in rat brain slices.

Product Info

Cas No.

132-17-2

Purity

≥99%

Formula

C21H25NO • CH4O3S

Formula Wt.

403.53

Chemical Name

3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane;methanesulfonic acid

IUPAC Name

3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane;methanesulfonic acid

Synonym

Cogentin mesylate

Solubility

Soluble in water (81 mg/ml at 25°C), DMSO (50 mg/ml at 25°C), ethanol (81 mg/ml at 25°C), and ether (very slightly).

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

B1955 MSDS PDF

Info Sheet

B1955 Info Sheet PDF

References

Ukairo OT, Bondi CD, Newman AH, et al. Recognition of benztropine by the dopamine transporter (DAT) differs from that of the classical dopamine uptake inhibitors cocaine, methylphenidate, and mazindol as a function of a DAT transmembrane 1 aspartic acid residue. J Pharmacol Exp Ther. 2005 Aug;314(2):575-83. PMID: 15879005.

Wieczorek WJ, Kruk ZL. A quantitative comparison on the effects of benztropine, cocaine and nomifensine on electrically evoked dopamine overflow and rate of re-uptake in the caudate putamen and nucleus accumbens in the rat brain slice. Brain Res. 1994 Sep 19;657(1-2):42-50. PMID: 7820642.

Custom Order

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