Description
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
| Cas No. | 1022958-60-6 |
|---|---|
| Purity | ≥98% |
| Formula | C28H35ClN6O3 |
| Formula Wt. | 539.08 |
| IUPAC Name | (1S,2S,3R,4R)-3-[(5-Chloro-2-{[(7S)-1-methoxy-7-(4-morpholinyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}-4-pyrimidinyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide |
| Synonym | CEP 28122, CEP28122 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Cheng M., Quail M., et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 11(3):670-79 (2012). PMID: 22203728.
Metabolite of spironolactone; Na+/K+ ATPase par...
mTOR inhibitor.
Endogenous peptide hormone fragment, involved i...
Found in Colchicum; microtubule polymerization ...
Organoselenium compound found in selenium-enric...
Prenylated phenolic terpene found in various pl...
Flavanol originally found in Camilla (green tea...
MEK1/2 inhibitor.
Peptide, neutral ionophore.
EGFR inhibitor.
Microtubule polymerization inhibitor.
Endogenous opioid peptide; δOR and μOR agonis...
Mycotoxin produced by species of Fusarium; pote...
Glycoprotein IIb/IIIa inhibitor.
SERT and NET inhibitor, Nav1.7 Na+ channel bloc...
EGFR inhibitor.
NET and SERT inhibitor, NMDA antagonist.
BHA derivative.
Cysteine-ITC conjugate, antioxidant; aldehyde d...
nNOS inhibitor.