Description
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
| Cas No. | 1022958-60-6 |
|---|---|
| Purity | ≥98% |
| Formula | C28H35ClN6O3 |
| Formula Wt. | 539.08 |
| IUPAC Name | (1S,2S,3R,4R)-3-[(5-Chloro-2-{[(7S)-1-methoxy-7-(4-morpholinyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}-4-pyrimidinyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide |
| Synonym | CEP 28122, CEP28122 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Cheng M., Quail M., et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 11(3):670-79 (2012). PMID: 22203728.
Proteinase subtrate.
TLR4 inhibitor.
Polyphenolic hydroxystilbene, resveratrol deri...
SERCA inhibitor.
Glycosaminoglycan
G-quadruplex ligand; DNA breakage inducer.
PPARγ coactivator-1α expression stimulator.
c-Raf inhibitor.
Endogenous prostaglandin, vasodilator.
JAK1 inhibitor.
Intermediate in the synthesis of purine analogs...
Microtubule polymerization inhibitor, potential...
Flavonoid glycoside found in fruit, asparagus, ...
β1/2-adrenergic antagonist.
Tyrphostin; IGF-1R inhibitor.
Calcium channel blocker.
Flavone found in Scutellaria; prolyl oligopepti...
inhibits inflammatory signaling
Cephalomannine derivative found in Taxus; poten...
Antimicrobial peptide found in bee and wasp ven...