Description
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
Product Unit Size | Cost | Quantity | Stock |
---|
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
Cas No. | 1022958-60-6 |
---|---|
Purity | ≥98% |
Formula | C28H35ClN6O3 |
Formula Wt. | 539.08 |
IUPAC Name | (1S,2S,3R,4R)-3-[(5-Chloro-2-{[(7S)-1-methoxy-7-(4-morpholinyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}-4-pyrimidinyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide |
Synonym | CEP 28122, CEP28122 |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Cheng M., Quail M., et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 11(3):670-79 (2012). PMID: 22203728.
Proteinase subtrate.
Protein translocation inhibitor.
NSAID; COX-1/2 inhibitor.
Furanolactone found in citrus fruits.
Flavonol found in fruits and vegetables; COMT i...
Fluoroquinolone, S-(-) isomer of ofloxacin; top...
Mycotoxin produced by Fusarium; sphingosine acy...
PI3K inhibitor.
β-lactam; penicillin binding protein inhibitor...
STING antagonist
Protein translation inhibitor.
Imidazoquinoline nucleoside analog; TLR-7/8 ago...
Catalyzes hydrolysis of asparagine.
Endogenous peptide hormone, involved in feeding...
EGFR inhibitor.
Nucleoside (deoxycytidine) analog; DNMT inhibit...
ALK5 (activin-like) inhibitor.
Aminoglycoside; protein translation inhibitor.<...
Endogenous neuropeptide, involved in energy hom...
Benzofuroxan derivative; MDMX inhibitor.