Description
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
| Cas No. | 1022958-60-6 |
|---|---|
| Purity | ≥98% |
| Formula | C28H35ClN6O3 |
| Formula Wt. | 539.08 |
| IUPAC Name | (1S,2S,3R,4R)-3-[(5-Chloro-2-{[(7S)-1-methoxy-7-(4-morpholinyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}-4-pyrimidinyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide |
| Synonym | CEP 28122, CEP28122 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Cheng M., Quail M., et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 11(3):670-79 (2012). PMID: 22203728.
Peptide, protease substrate.
Pyramido-pyrrolo-quinoxalinedione; CFTR blocker...
SERT inhibitor, potential voltage-gated K+ chan...
Synthesis intermediate
Iridoid glycoside found in Gardenia.
Multikinase inhibitor.
5-HT2 antagonist, SERT and NET inhibitor, hERG ...
Endogenous steroid hormone, estriol precursor; ...
Statin; HMG-CoA reductase inhibitor.
Triterpene saponin found in Bupleurum.
Flavanone found in species of Citrus; L-type Ca...
Histamine H1-antagonist
Thio sulforaphane analog, ITC.
Fatty acid synthase inhibitor.
EGFR inhibitor.