Description
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
Product Unit Size | Cost | Quantity | Stock |
---|
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
Cas No. | 1022958-60-6 |
---|---|
Purity | ≥98% |
Formula | C28H35ClN6O3 |
Formula Wt. | 539.08 |
IUPAC Name | (1S,2S,3R,4R)-3-[(5-Chloro-2-{[(7S)-1-methoxy-7-(4-morpholinyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}-4-pyrimidinyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide |
Synonym | CEP 28122, CEP28122 |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Cheng M., Quail M., et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 11(3):670-79 (2012). PMID: 22203728.
Alkaloid found in Galanthus, Narcissus, Leucoju...
PI3K inhibitor.
Imidzoline derivative; MDM2 inhibitor.
NSAID; COX-2 inhibitor.
Nitrosourea, DNA alkylator.
Islet α/β cell proliferation stimulator.
Aldehyde dehydrogenase, 26S proteasome, MGMT in...
ROCK1/2 inhibitor.
Cysteine-ITC conjugate, antioxidant; HDAC inhib...
FIASMA, 5-HT3 and σ1 agonist, SERT inhibitor.<...
Found in Paeonia; L-type Ca2+ channel blocker.<...
NNK precursor found in tobacco smoke; carcinoge...
Diterpene vitamin A; RAR/RXR agonist.
p110δ PI3K inhibitor.
Mycotoxin produced by species of Aspergillus; D...
Tropane alkaloid found in Solanaceae plants; M1...
Peptide; calcineurin inhibitor.
Taxane synthesis intermediate.
Camptothecin derivative; topoisomerase I inhibi...
Valsartan impurity