Description
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
Product Unit Size | Cost | Quantity | Stock |
---|
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
Cas No. | 1022958-60-6 |
---|---|
Purity | ≥98% |
Formula | C28H35ClN6O3 |
Formula Wt. | 539.08 |
IUPAC Name | (1S,2S,3R,4R)-3-[(5-Chloro-2-{[(7S)-1-methoxy-7-(4-morpholinyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}-4-pyrimidinyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide |
Synonym | CEP 28122, CEP28122 |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Cheng M., Quail M., et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 11(3):670-79 (2012). PMID: 22203728.
Endogenous steroid hormone involved in stress s...
Dihydropyrazine found in Ligusticum walliichi. ...
Coumarin; VKORC1 inhibitor.
Glycolic acid ester prodrug of indomethacin, NS...
Cell membrane permeability modulator, topoisome...
Allylbenzene found in spices and umbelliferous ...
Kavalactone originally found in Piper methystic...
Polyphenol found in various plants and foods.
Steroid; glucocorticoid agonist.
Broad-spectrum antiviral activity against SARS-...
Found in Cephalosporium; fatty acid synthase in...
Alkaloid found in Corydalis and Stephania; D1/2...
Peptide, involved in neutrophil activation; FPR...
Alkaloid found in Fabaceae family plants; α3β...
β-lactamase inhibitor.
Geldanamycin derivative; HSP90 inhibitor.
Alkaloid found in Corydalis; D1 antagonist, org...
Nucleoside (guanosine) analog; DNA chain termin...
Diaminoquinazoline derivative.
Perfluorinated insecticide.