Description
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
| Cas No. | 1022958-60-6 |
|---|---|
| Purity | ≥98% |
| Formula | C28H35ClN6O3 |
| Formula Wt. | 539.08 |
| IUPAC Name | (1S,2S,3R,4R)-3-[(5-Chloro-2-{[(7S)-1-methoxy-7-(4-morpholinyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}-4-pyrimidinyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide |
| Synonym | CEP 28122, CEP28122 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Cheng M., Quail M., et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 11(3):670-79 (2012). PMID: 22203728.
Cdc42 GTPase inhibitor.
Sulfur analog of furan found in cooked meat pro...
Flavonoid found in various plant sources; DAT a...
Unlikely to reverse Alzheimer’s
BH3 mimetic; Bcl-2 inhibitor.
Iridoid glycoside found in Gardinia jasminoides...
Endogenous peptide hormone fragment, involved i...
Phytoalexin, indole found in cruciferous vegeta...
Inhibitor of CDK.
1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhi...
H+/K+ ATPase and ROCK-2 inhibitor.
Cysteine conjugate of benzyl isothiocyanate (BI...
Synthetic peptide, vasopressin derivative; V2 a...
Endogenous peptide, involved in immune signalin...
Macrolide antibiotic; vacuolar H+ ATPase inhibi...
NSAID; COX-1/2 and lipoxygenase inhibitor.
Micronuclei formation inducer, antimitotic, oxi...
Recombinant Multi-epitope Chimeric HCV antigen....
Mixture of pyrantel, a thiophene, and pamoic ac...
Pheniramine derivative; histamine H1 and mAChR ...