Description
CUDC-907 (Fimepinostat) is an inhibitor of PI3K and class I and II histone deacetylases (HDACs). This compound exhibits anticancer chemotherapeutic activity, inhibiting cell proliferation and tumor growth in a variety of cancer models.
| Product Unit Size | Cost | Quantity | Stock |
|---|
CUDC-907 (Fimepinostat) is an inhibitor of PI3K and class I and II histone deacetylases (HDACs). This compound exhibits anticancer chemotherapeutic activity, inhibiting cell proliferation and tumor growth in a variety of cancer models.
| Cas No. | 1339928-25-4 |
|---|---|
| Purity | ≥98% |
| Formula | C23H24N8O4S |
| Formula Wt. | 508.55 |
| Chemical Name | Fimepinostat |
| IUPAC Name | N-hydroxy-2-[[2-(6-methoxypyridin-3-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl-methylamino]pyrimidine-5-carboxamide |
| Synonym | Fimepinostat; CUDC 907; CUDC907 |
| Solubility | DMSO 102 mg/mL (200.57 mM) Water Insoluble Ethanol Insoluble |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Qian C, Lai CJ, Bao R, et al. Cancer network disruption by a single molecule inhibitor targeting both histone deacetylase activity and phosphatidylinositol 3-kinase signaling. Clin Cancer Res. 2012 Aug 1;18(15):4104-13. PMID: 22693356.
Nitrogen mustard, DNA alkylator.
FIASMA, μOR agonist, potential HCN channel blo...
HPGDS inhibitor.
Polyphenol found in various plant sources, resv...
Flavonoid glycoside found in citrus fruit.
Topoisomerase II inhibitor, RPA modulator.
BUB1 inhibitor.
EGFR, VEGFR inhibitor.
Aminoglycoside; protein translation inhibitor.<...
Mcl-1 inhibitor
Carotenoid found in shrimp, salmon, and algae.<...
Synthesis impurity
RAF inhibitor.
Loop diuretic; NKCC symporter and KCC2 co-trans...
Macrolide; F1F0 ATP synthase inhibitor.
Triterpene saponin found in species of Panax; P...
Bisphosphonate; FPPS inhibitor.
Water-soluble cortisol derivative; glucocortico...
Thienylbutyl ITC analog.
Polyphenol found in many plants and foods.