Description
CUDC-907 (Fimepinostat) is an inhibitor of PI3K and class I and II histone deacetylases (HDACs). This compound exhibits anticancer chemotherapeutic activity, inhibiting cell proliferation and tumor growth in a variety of cancer models.
Product Unit Size | Cost | Quantity | Stock |
---|
CUDC-907 (Fimepinostat) is an inhibitor of PI3K and class I and II histone deacetylases (HDACs). This compound exhibits anticancer chemotherapeutic activity, inhibiting cell proliferation and tumor growth in a variety of cancer models.
Cas No. | 1339928-25-4 |
---|---|
Purity | ≥98% |
Formula | C23H24N8O4S |
Formula Wt. | 508.55 |
Chemical Name | Fimepinostat |
IUPAC Name | N-hydroxy-2-[[2-(6-methoxypyridin-3-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl-methylamino]pyrimidine-5-carboxamide |
Synonym | Fimepinostat; CUDC 907; CUDC907 |
Solubility | DMSO 102 mg/mL (200.57 mM) Water Insoluble Ethanol Insoluble |
Appearance | White Crystal Powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Qian C, Lai CJ, Bao R, et al. Cancer network disruption by a single molecule inhibitor targeting both histone deacetylase activity and phosphatidylinositol 3-kinase signaling. Clin Cancer Res. 2012 Aug 1;18(15):4104-13. PMID: 22693356.
FIASMA, SERT and NET inhibitor, mAChR antagonis...
FAK inhibitor.
Triterpene saponin found in species of Panax.
Diterpene alkaloid found in Aconitum; voltage-g...
Highly selective inhibitor
5-fluorouracil prodrug, pyrimidine analog; thym...
Quinoline; PDE 3B inhibitor.
Neurotoxin frequently used to aid in modeling P...
ITC, erucin analog.
p110α PI3K inhibitor.
Sulfonylurea; ATP-sensitive K+ channel blocker....
AMPK activator, L-type Ca2+ channel and NMDA, h...
Neuromodulator, biomarker
Nucleoside (thymidine) analog; DNA chain termin...
ATP-sensitive K+ channel activator, α-adrenerg...
BHA derivative, cellular differentiation induce...
Diterpene found in coffee beans.
Endogenous peptide hormone; guanyl cyclase C ag...
Serum response factor inhibitor and MRTF-A bind...
Saponin found in Bupleurum, Heteromorpha, and S...