Description
CUDC-907 (Fimepinostat) is an inhibitor of PI3K and class I and II histone deacetylases (HDACs). This compound exhibits anticancer chemotherapeutic activity, inhibiting cell proliferation and tumor growth in a variety of cancer models.
| Product Unit Size | Cost | Quantity | Stock |
|---|
CUDC-907 (Fimepinostat) is an inhibitor of PI3K and class I and II histone deacetylases (HDACs). This compound exhibits anticancer chemotherapeutic activity, inhibiting cell proliferation and tumor growth in a variety of cancer models.
| Cas No. | 1339928-25-4 |
|---|---|
| Purity | ≥98% |
| Formula | C23H24N8O4S |
| Formula Wt. | 508.55 |
| Chemical Name | Fimepinostat |
| IUPAC Name | N-hydroxy-2-[[2-(6-methoxypyridin-3-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl-methylamino]pyrimidine-5-carboxamide |
| Synonym | Fimepinostat; CUDC 907; CUDC907 |
| Solubility | DMSO 102 mg/mL (200.57 mM) Water Insoluble Ethanol Insoluble |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Qian C, Lai CJ, Bao R, et al. Cancer network disruption by a single molecule inhibitor targeting both histone deacetylase activity and phosphatidylinositol 3-kinase signaling. Clin Cancer Res. 2012 Aug 1;18(15):4104-13. PMID: 22693356.
Monoterpene found in various plant sources.
Endogenous opioid peptide; μOR agonist.
Thiazolidine macrolide found in the Red Sea spo...
Dynamin inhibitor.
Endogenous neuropeptide involved in hormone rel...
Selective estrogen receptor modulator.
ITC, used as chiral agent.
Alkaloid found in Catharanthus, precursor in sy...
Chalcone kavalactone found in Piper methysticum...
ACE inhibitor.
Phytoestrogen, isoflavone found in various plan...
Amino acid precursor of dopamine.
D2 and D4 dopamine receptor inhibitor.
mTOR inhibitor.
Derivative of methyl caffeate, hydroxycinnamic ...
Endogenous peptide hormone; motilin agonist.
Found in Aristolochia and Radix; potential PLA2...
Alkaloid found in Sophora.
PI3K inhibitor, microtubule polymerization inhi...
Diterpene acid found in Pseudolarix kaempferi.<...