Description
CUDC-907 (Fimepinostat) is an inhibitor of PI3K and class I and II histone deacetylases (HDACs). This compound exhibits anticancer chemotherapeutic activity, inhibiting cell proliferation and tumor growth in a variety of cancer models.
| Product Unit Size | Cost | Quantity | Stock |
|---|
CUDC-907 (Fimepinostat) is an inhibitor of PI3K and class I and II histone deacetylases (HDACs). This compound exhibits anticancer chemotherapeutic activity, inhibiting cell proliferation and tumor growth in a variety of cancer models.
| Cas No. | 1339928-25-4 |
|---|---|
| Purity | ≥98% |
| Formula | C23H24N8O4S |
| Formula Wt. | 508.55 |
| Chemical Name | Fimepinostat |
| IUPAC Name | N-hydroxy-2-[[2-(6-methoxypyridin-3-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl-methylamino]pyrimidine-5-carboxamide |
| Synonym | Fimepinostat; CUDC 907; CUDC907 |
| Solubility | DMSO 102 mg/mL (200.57 mM) Water Insoluble Ethanol Insoluble |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Qian C, Lai CJ, Bao R, et al. Cancer network disruption by a single molecule inhibitor targeting both histone deacetylase activity and phosphatidylinositol 3-kinase signaling. Clin Cancer Res. 2012 Aug 1;18(15):4104-13. PMID: 22693356.
Chloramphenicol derivative; protein translation...
Anthraquinone found in Rheum.
Pt-based DNA cross-linker.
Salicylic acid derivative; PPARγ agonist, pote...
Azapirone; α1-adrenergic and 5-HT1A partial ag...
Cationic antimicrobial peptide, alters bacteria...
B-Raf inhibitor.
Reduces production of thyroid hormones
Wnt/beta-catenin/CBP inhibitor
CDK4/6 inhibitor.
Pyramido-pyrrolo-quinoxalinedione; CFTR blocker...
Derivative of methyl caffeate, hydroxycinnamic ...
Phytoestrogen, flavonoid found in clover, soy, ...
Mycotoxin produced by Fusarium fungi that infec...
Glycopeptide, induces DNA strand breaks.
Vinca alkaloid found in Catharanthus; microtubu...
O-methylated coumarin; Ca2+ channel blocker.
Steroid 5-α-reductase inhibitor.