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GW 405833

GW 405833

Product ID G880000
Cas No. 180002-83-9
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $64.50 Please Inquire
5 mg $157.40 Please Inquire
25 mg $465.20 In stock
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Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

GW405833 is a selective cannabinoid receptor 2 (CB2) agonist. It shows activity in pancreatic cancer mouse models and reduces the number of Ca2+ ocilllations in pancreatic acinar cells, which is a cause of pancreatitis.

Product Info

Cas No.

180002-83-9

Purity

≥98%

Formula

C23H24Cl2N2O3

Formula Wt.

447.356

Chemical Name

(2,3-dichlorophenyl)-[5-methoxy-2-methyl-3-(2-morpholin-4-ylethyl)indol-1-yl]methanone

IUPAC Name

(2,3-dichlorophenyl)-[5-methoxy-2-methyl-3-(2-morpholin-4-ylethyl)indol-1-yl]methanone

Synonym

L-768,242, GW405833

Solubility

50mM in DMSO, 50mM in ethanol

Appearance

Tan powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G880000 MSDS PDF

Info Sheet

G880000 Info Sheet PDF

References

Huang Z, Wang H, Wang J et al. Cannabinoid receptor subtype 2 (CB2R) agonist, GW405833 reduces agonist-induced Ca(2+) oscillations in mouse pancreatic acinar cells. Sci Rep. 2016 Jul 19:6:29757. PMID: 27432473.

Mancini I, Brusa R, Quadrato G et al. Constitutive activity of cannabinoid-2 (CB2) receptors plays an essential role in the protean agonism of (+)AM1241 and L768242. Br J Pharmacol. 2009 Sep;158(1):382-91. PMID: 19552692.

Custom Order

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