LKT Labs

Biochemicals for Life Science Research

Hydrocortisone

Hydrocortisone

Product ID H9611
Cas No. 50-23-7
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $141.00 In stock
10 g $241.00 In stock
25 g $481.00 In stock
Bulk Quote

Quicklinks

Description

Hydrocortisone is a steroid hormone that is produced in the adrenal cortex and is involved in stress signaling. Hydrocortisone is a glucocorticoid and is also known as cortisol in its endogenous form; it exhibits anti-inflammatory and immunomodulatory activities. Hydrocortisone is clinically used to treat eczema, psoriasis, gout, and severe allergic reactions. Hydrocortisone stimulates gluconeogenesis, inhibits inflammatory cytokine production, and shifts the immune response from Th1 to Th2 subtype.

Product Info

Cas No.

50-23-7
Purity

≥98%
Formula

C21H30O5
Formula Wt.

362.46
Chemical Name

(11β)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
IUPAC Name

(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10, 13-dimethyl-2,6,7,8,9,11,12,14,15, 16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Synonym

Cortisol, Anflam, Dermacortal, Efcortelan, Ficortril, Hydracort, Medicort, Penecort, Texacort, Zenoxone
Melting Point

217-220°C

Solubility

Soluble in ethanol (25 mg/mL), acetone (12 mg/mL), or propylene glycol. Very slightly soluble in ether or water.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

H9611 MSDS PDF
Info Sheet

H9611 Info Sheet PDF

References

Angelier F, Wingfield JC. Importance of the glucocorticoid stress response in a changing world: theory, hypotheses and perspectives. Gen Comp Endocrinol. 2013 Sep 1;190:118-28. PMID: 23770214.

Tarchalska-Kryńska B. Glucocorticosteroids: mechanism of action, pharmacological effects, pharmacokinetics and adverse effects. Otolaryngol Pol. 1994;48 Suppl 17:41-8. PMID: 8090502.

Sluyser M. Mechanism of steroid hormone action at the cellular level. Basic Life Sci. 1975;6:79-104. PMID:168860.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • N7200

    NS-11394

    GABA-A α5/3/2 positive modulator.

    ≥98%
  • S584780

    Sotorasib racemate

    KRAS inhibitor

    ≥99%
  • L1786

    Levofloxacin Hydrochloride Monohydrate

    Fluoroquinolone, S-(-) isomer of ofloxacin; top...

    ≥90%
  • R1777

    9-cis-Retinoic Acid

    Vitamin A derivative; RAR and RXR agonist.

    ≥99%
  • G1853

    Genipin

    Iridoid glycoside found in Gardinia jasminoides...

    ≥99%
  • N8460

    NVP-BHG712

    EphB4 inhibitor.

    ≥98%
  • T1754

    Tenatoprazole

    H+/K+ ATPase inhibitor.

    ≥98%
  • V1869

    Verbascoside

    Phenylpropanoid found in Castilleja, Verbena, V...

    ≥98%
  • G691343

    Griseofulvin

    Fungistatic

    ≥98%
  • M1669

    6-Mercaptopurine Monohydrate

    Thiopurine antimetabolite; PRPP amidotransferas...

    ≥98%
  • B8070

    2-tert-Butyl-4-Hydroxyanisole

    BHA derivative, antioxidative food and cosmetic...

    ≥99% single isomer
  • D324090

    Diclofenac Impurity C

    Impurity of diclofenac

    ≥98%
  • G4518

    Glucaric Acid Calcium Tetrahydrate

    Oxidized non-cylic hexose sugar.

    ≥98%
  • D183745

    Destruxin B

    Cyclic depsipeptide is a secondary metabolite i...

    ≥96%
  • C0148

    Calcitonin, human

    Endogenous neuropeptide hormone, lowers extrace...

    ≥95%
  • T6935

    Trimebutine Base

    BK K+ channel and L-type Ca2+ channel blocker.<...

    ≥97%
  • R1877

    all-trans-Retinol, ≥98 %

    Diterpene vitamin A; RAR/RXR agonist.

    ≥98%
  • M0125

    Magnolol

    Lignan found in Magnolia; GABA-A potentiator.

    ≥98%
  • N0062

    D,L-Naproxen

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • E6356

    Epothilone D

    Microtubule depolymerization inhibitor.

    ≥98%