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Hydrocortisone

Hydrocortisone

Product ID H9611
Cas No. 50-23-7
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $140.70 In stock
10 g $240.70 In stock
25 g $481.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Hydrocortisone is a steroid hormone that is produced in the adrenal cortex and is involved in stress signaling. Hydrocortisone is a glucocorticoid and is also known as cortisol in its endogenous form; it exhibits anti-inflammatory and immunomodulatory activities. Hydrocortisone is clinically used to treat eczema, psoriasis, gout, and severe allergic reactions. Hydrocortisone stimulates gluconeogenesis, inhibits inflammatory cytokine production, and shifts the immune response from Th1 to Th2 subtype.

Product Info

Cas No.

50-23-7

Purity

≥98%

Formula

C21H30O5

Formula Wt.

362.46

Chemical Name

(11β)-11,17,21-Trihydroxypregn-4-ene-3,20-dione

IUPAC Name

(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10, 13-dimethyl-2,6,7,8,9,11,12,14,15, 16-decahydro-1H-cyclopenta[a]phenanthren-3-one

Synonym

Cortisol, Anflam, Dermacortal, Efcortelan, Ficortril, Hydracort, Medicort, Penecort, Texacort, Zenoxone

Melting Point

217-220°C

Solubility

Soluble in ethanol (25 mg/mL), acetone (12 mg/mL), or propylene glycol. Very slightly soluble in ether or water.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

H9611 MSDS PDF

Info Sheet

H9611 Info Sheet PDF

References

Angelier F, Wingfield JC. Importance of the glucocorticoid stress response in a changing world: theory, hypotheses and perspectives. Gen Comp Endocrinol. 2013 Sep 1;190:118-28. PMID: 23770214.

Tarchalska-Kryńska B. Glucocorticosteroids: mechanism of action, pharmacological effects, pharmacokinetics and adverse effects. Otolaryngol Pol. 1994;48 Suppl 17:41-8. PMID: 8090502.

Sluyser M. Mechanism of steroid hormone action at the cellular level. Basic Life Sci. 1975;6:79-104. PMID:168860.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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