Description
KB-0742 is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models.
| Product Unit Size | Cost | Quantity | Stock |
|---|
KB-0742 is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models.
| Cas No. | 2170137-61-6 (free base) |
|---|---|
| Purity | ≥98% |
| Formula | C16H25N5 |
| Formula Wt. | 287.41 |
| IUPAC Name | (1S,3S)-3-N-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine |
| Synonym | KB0742, NSC-834161, NSC834161 |
| Appearance | Yellow to brown crystal |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Richters A, Doyle S, Freeman D, et al. Modulating androgen receptor-driven transcription in prostate cancer with selective CDK9 inhibitors. Cell Chem Biol. 2021 Feb 18;28(2):134-147. PMID: 33086052
PORCN inhibitor.
Phytoestrogen, isoflavone found in various plan...
Hydantoin derivative; RyR antagonist, L-type Ca...
Thiazolidinedione; PPARγ agonist.
Endogenous peptide involved in vascular contrac...
VEGF-C/Nrp2 inhibitor. Leukotriene receptor ant...
Fatty acid found in dairy products; HDAC inhibi...
Pesticide; demethylation inhibitor.
Sesquiterpene found in various plant sources. <...
σ1 antagonist.
Synthetic prednisolone prodrug; glucocorticoid ...
Polyanionic sulfated glycosaminoglycan, encogen...
Peptide fragment of VSV; LDLR agonist.
Endogenous peptide hormone, involved in water h...
Peptide, urocortin III analog; CRFR2 agonist.
Bipyridamine toxin.
Inhibitor of glutamic acid decarboxylase (GAD)....
LRRK2 inhibitor.
Flavanol originally found in Camilla (green tea...
PI3K and HDAC inhibitor.