Description
KB-0742 is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models.
| Product Unit Size | Cost | Quantity | Stock |
|---|
KB-0742 is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models.
| Cas No. | 2170137-61-6 (free base) |
|---|---|
| Purity | ≥98% |
| Formula | C16H25N5 |
| Formula Wt. | 287.41 |
| IUPAC Name | (1S,3S)-3-N-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine |
| Synonym | KB0742, NSC-834161, NSC834161 |
| Appearance | Yellow to brown crystal |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Richters A, Doyle S, Freeman D, et al. Modulating androgen receptor-driven transcription in prostate cancer with selective CDK9 inhibitors. Cell Chem Biol. 2021 Feb 18;28(2):134-147. PMID: 33086052
Wnt signaling inhibitor.
Reduces production of thyroid hormones
Cathepsin K inhibitor.
VEGFR inhibitor.
Mineralocorticoid, aldosterone, AR antagonist, ...
ALK, ROS1, c-MET inhibitor.
HIV integrase inhibitor.
Trichothecene mycotoxin produced by Fusarium.
Fat-soluble vitamin C derivative.
p38 MAPK inhibitor.
Alkaloid originally found in species of Aconitu...
Endogenous peptide, cleavage product of AT II; ...
β-lactam cephalosporin; penicillin binding pro...
Semi-synthetic vinca alkaloid found in Catharan...
Azalide macrolide; protein translation inhibito...
CB1 agonist, TRPV1 agonist.
Geldanamycin derivative; HSP90 inhibitor.
Allosteric inhibitor
Pt-based DNA cross-linker.
Thiazolidine macrolide found in the Red Sea spo...