Description
KB-0742 is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models.
Product Unit Size | Cost | Quantity | Stock |
---|
KB-0742 is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models.
Cas No. | 2170137-61-6 (free base) |
---|---|
Purity | ≥98% |
Formula | C16H25N5 |
Formula Wt. | 287.41 |
IUPAC Name | (1S,3S)-3-N-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine |
Synonym | KB0742, NSC-834161, NSC834161 |
Appearance | Yellow to brown crystal |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
Info Sheet |
---|
Richters A, Doyle S, Freeman D, et al. Modulating androgen receptor-driven transcription in prostate cancer with selective CDK9 inhibitors. Cell Chem Biol. 2021 Feb 18;28(2):134-147. PMID: 33086052
Endogenous peptide, involved in hormone regulat...
Antioxidant shown to improve renal function.
Semi-synthetic derivative of chlorophyll; food ...
PI3K inhibitor.
STING agonist
Dihydropyridine; L-type and T-type Ca2+ channel...
InsR and IGF-1R inhibitor.
Inhibitor of EGFR/HER2 (ErbB2).
Hydantoin derivative; RyR antagonist, L-type Ca...
Purine derivative; CDK inhibitor.
ITC, erucin analog.
Oxyindole alkaloid found in Uncaria sinensis; h...
5-HT1A agonist, 5-HT2A antagonist.
2-methyl-1,4-naphthoquinone derivative
Non-endogenous essential vitamin (B9), found in...
Synthetic peptide hormone.
ITC.
Nitrogen mustard, DNA alkylator.
SERT and NET inhibitor, Nav1.7 Na+ channel bloc...
MurA and isopentenyl mevalonate kinase inhibito...