Description
KB-0742 is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models.
| Product Unit Size | Cost | Quantity | Stock |
|---|
KB-0742 is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models.
| Cas No. | 2170137-61-6 (free base) |
|---|---|
| Purity | ≥98% |
| Formula | C16H25N5 |
| Formula Wt. | 287.41 |
| IUPAC Name | (1S,3S)-3-N-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine |
| Synonym | KB0742, NSC-834161, NSC834161 |
| Appearance | Yellow to brown crystal |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Richters A, Doyle S, Freeman D, et al. Modulating androgen receptor-driven transcription in prostate cancer with selective CDK9 inhibitors. Cell Chem Biol. 2021 Feb 18;28(2):134-147. PMID: 33086052
Non-selective HDAC inhibitor.
VEGFR1/2/3, TIE2, PDGFRβ, FGFR1, c-Kit, RET, B...
N-Des-2-methylpropan-2-ol Docetaxel is an impur...
Macrolide; F1F0 ATP synthase inhibitor.
5-HT2 antagonist, SERT and NET inhibitor, hERG ...
Histamine H2 inverse agonist.
Peptide, substance P analog; NK agonist.
Endogenous peptide hormone fragment, involved i...
HDAC inhibitor, mammalian RNA splicing modulato...
Inhibitor of Bruton’s tyrosine kinase (BTK).<...
Fermentation impurity
AurKB/C inhibitor.
M4 mAChR agonist, 5-HT1A partial agonist, M1/2/...
PARP inhibitor; potential Pim1 inhibitor.
β-lactam; penicillin binding protein inhibitor...
Topoisomerase II inhibitor, RPA modulator.
Lincosamide; ribosomal translocation and protei...
Derivative of methyl caffeate, hydroxycinnamic ...
Histamine H1 antagonist, FIASMA.
c-Raf inhibitor, tyrosine kinase inhibitor.