Description
KB-0742 is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models.
| Product Unit Size | Cost | Quantity | Stock |
|---|
KB-0742 is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models.
| Cas No. | 2170137-61-6 (free base) |
|---|---|
| Purity | ≥98% |
| Formula | C16H25N5 |
| Formula Wt. | 287.41 |
| IUPAC Name | (1S,3S)-3-N-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine |
| Synonym | KB0742, NSC-834161, NSC834161 |
| Appearance | Yellow to brown crystal |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Richters A, Doyle S, Freeman D, et al. Modulating androgen receptor-driven transcription in prostate cancer with selective CDK9 inhibitors. Cell Chem Biol. 2021 Feb 18;28(2):134-147. PMID: 33086052
CRTH2 inhibitor.
Benzimidazole; microtubule polymerization inhib...
BHA derivative, antioxidative food and cosmetic...
Targets nuclear factor kappa B activation.
Synthetic progestogen; contraceptive.
Fluoroquinolone; topoisomerase IV and bacterial...
MELK inhibitor.
D2 and 5-HT2A antagonist.
Endogenous peptide hormone, involved in stress ...
GHS-R1a agonist, γ-secretase inhibitor.
CHK1 inhibitor.
Synthetic somatostatin analog, peptide; somatos...
NSAID; COX-1/2 inhibitor.
Induces activation of Nrf2; inhibits apoptosis ...
Diterpene found in brewed, unfiltered coffee; F...
FIASMA, L-type Ca2+ channel blocker, D2 antagon...
AKT inhibitor, potential ROCK, p70S6K, PKA, MKK...
Sesquiterpene lactone found in Ginkgo; GABA-A a...
Sesquiterpene lactone found in Artemisia (wormw...
Pleuromutilin