Description
KB-0742 is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models.
Product Unit Size | Cost | Quantity | Stock |
---|
KB-0742 is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models.
Cas No. | 2170137-61-6 (free base) |
---|---|
Purity | ≥98% |
Formula | C16H25N5 |
Formula Wt. | 287.41 |
IUPAC Name | (1S,3S)-3-N-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine |
Synonym | KB0742, NSC-834161, NSC834161 |
Appearance | Yellow to brown crystal |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
Info Sheet |
---|
Richters A, Doyle S, Freeman D, et al. Modulating androgen receptor-driven transcription in prostate cancer with selective CDK9 inhibitors. Cell Chem Biol. 2021 Feb 18;28(2):134-147. PMID: 33086052
Aldehyde dehydrogenase, 26S proteasome, MGMT in...
Vitamin B, required for formation of NAD and NA...
Fluoroquinolone; bacterial DNA gyrase inhibitor...
Antioxidant, vitamin E derivative found in vege...
p38 MAPK inhibitor.
Synthesis intermediate
ITC.
Arabinosyl transferase inhibitor.
Endogenous peptide, cleavage product of AT II; ...
Synthetic ITC.
MET inhibitor.
Bisindole isomer of indigo found in Indigo natu...
Flavonoid originally found in Silybum (milk thi...
NSAID; COX-1/2 inhibitor.
β-lactam carbapenem; penicillin binding protei...
Non-opioid analgesic.
Neuropeptide hormone found in insects, involved...
Saponin found in Bupleurum, Heteromorpha, and S...
Synthetic peptide, fibrinogen derivative; glyco...
ITC found in cruciferous vegetables.