• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Lisinopril Dihydrate

Lisinopril Dihydrate

Product ID L3374
Cas No. 83915-83-7
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $71.50 In stock
1 g $142.90 In stock
5 g $408.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Lisinopril is an enalapril analog that inhibits angiotensin-converting enzyme (ACE), exhibiting antihypertensive, cardioprotective, and anti-fibrotic activities. Lisinopril is clinically used to treat hypertension, congestive heart failure (CHF), myocardial infarction, and retinal disorders associated with diabetes. In vivo, lisinopril decreases matrix metalloproteinase 2 (MMP2) activity, inhibits left ventricular dilation, and suppresses myocardial hypertrophy, preventing changes in contractility. In other animal models, this compound decreases hydroxyproline levels and inhibits paraquat-induced lung fibrosis.

Product Info

Cas No.

83915-83-7

Purity

≥98%

Formula

C21H31N3O5 • 2H2O

Formula Wt.

441.52

Chemical Name

(S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]- proline dihydrate

IUPAC Name

(2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl] pyrrolidine-2-carboxylic acid;dihydrate

Synonym

Acerbon, Carace, Coric, Novatec, Prinil, Tensopril, Vivatec, Zestril

Melting Point

160°C (dec)

Solubility

Soluble in water (100 mg/mL) or DMSO (6.5mg/mL with heating and sonication), methanol (14 mg/mL). Insoluble in ethanol.

Appearance

White or almost white crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

L3374 MSDS PDF

Info Sheet

L3374 Info Sheet PDF

References

Brower GL, Levick SP, Janicki JS. Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3057-64. PMID: 17308006.

Mohammadi-Karakani A, Ghazi-Khansari M, Sotoudeh M. Lisinopril ameliorates paraquat-induced lung fibrosis. Clin Chim Acta. 2006 May;367(1-2):170-4. PMID: 16458281.

Goa KL, Balfour JA, Zuanetti G. Lisinopril. A review of its pharmacology and clinical efficacy in the early management of acute myocardial infarction. Drugs. 1996 Oct;52(4):564-88. PMID: 8891468.

Apostolakis S, Krambovitis E, Vlata Z, et al. CX3CR1 receptor is up-regulated in monocytes of coronary artery diseased patients: impact of pre-inflammatory stimuli and renin-angiotensin system modulators. Thromb Res. 2007;121(3):387-395. PMID: 17521710.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • N7200

    NS-11394

    GABA-A α5/3/2 positive modulator.

    ≥98%
  • N1873

    Nesiritide Acetate

    Recombinant BNP, cardiomodulatory peptide; NPR-...

    ≥95%
  • K2412

    KGDS

    Synthetic peptide, fibrinogen derivative; glyco...

    ≥95%
  • D9752

    Dynasore

    Dynamin inhibitor.

    ≥98%
  • T5870

    Torin 1

    Tricyclic benzonaphthyridinone; mTORC1/2 inhibi...

    ≥98%
  • B0133

    Baicalin

    Flavone found in Scutellaria; prolyl oligopepti...

    ≥95%
  • G7444

    GSK-1070916

    AurKB/C inhibitor.

    ≥98%
  • B8174

    Butylated Hydroxyanisole

    Commercial food additive, antioxidant.

    ≥96%
  • M9356

    Myomodulin

    Proton pump inhibitor

    ≥95%
  • R0154

    Ranolazine Dihydrochloride

    Nav1.7 and Nav1.8 N1+ channel blocker.

    ≥98%
  • S7601

    Statil

    Aldose reductase inhibitor.

    ≥98%
  • T286161

    Theaflavin

    Polyphenolic compound present in black tea.

    ≥98%
  • O9302

    Oxacillin Sodium Monohydrate

    β-lactam; penicillin binding protein inhibitor...

    ≥98%
  • C6132

    CPI-203

    Triazolothienodiazepine, JQ-1 derivative; BRD i...

    ≥98%
  • S760004

    Stachybotrylactam

    Spirodihydrobenzofuranlactam

    ≥98%
  • B0108

    Bactenecin

    Cathelicidin derivative, antimicrobial peptide,...

    ≥95%
  • B1753

    Benfotiamine

    Thiamine/vitamin B derivative, antioxidant.

    ≥98%
  • C0251

    Calcitonin Gene Related Peptide II, rat

    Calcitonin-family peptide, involved in vasodila...

    ≥95%
  • D0262

    Dapiprazole Hydrochloride

    α1-Adrenergic antagonist.

    ≥98%
  • N1986

    Neuropeptide Y, human/rat

    Endogenous peptide neurotransmitter, involved i...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only