Lisinopril Dihydrate

Name: Lisinopril Dihydrate
SKU: L3374
Availability: InStock

Product ID L3374

Cas No. 83915-83-7

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Lisinopril is an enalapril analog that inhibits angiotensin-converting enzyme (ACE), exhibiting antihypertensive, cardioprotective, and anti-fibrotic activities. Lisinopril is clinically used to treat hypertension, congestive heart failure (CHF), myocardial infarction, and retinal disorders associated with diabetes. In vivo, lisinopril decreases matrix metalloproteinase 2 (MMP2) activity, inhibits left ventricular dilation, and suppresses myocardial hypertrophy, preventing changes in contractility. In other animal models, this compound decreases hydroxyproline levels and inhibits paraquat-induced lung fibrosis.

Product Info

Cas No.	83915-83-7
Purity	≥98%
Formula	C₂₁H₃₁N₃O₅ • 2H₂O
Formula Wt.	441.52
Chemical Name	(S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]- proline dihydrate
IUPAC Name	(2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl] pyrrolidine-2-carboxylic acid;dihydrate
Synonym	Acerbon, Carace, Coric, Novatec, Prinil, Tensopril, Vivatec, Zestril
Melting Point	160°C (dec)
Solubility	Soluble in water (100 mg/mL) or DMSO (6.5mg/mL with heating and sonication), methanol (14 mg/mL). Insoluble in ethanol.
Appearance	White or almost white crystalline powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	L3374 MSDS PDF
Info Sheet	L3374 Info Sheet PDF

References

Brower GL, Levick SP, Janicki JS. Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3057-64. PMID: 17308006.

Mohammadi-Karakani A, Ghazi-Khansari M, Sotoudeh M. Lisinopril ameliorates paraquat-induced lung fibrosis. Clin Chim Acta. 2006 May;367(1-2):170-4. PMID: 16458281.

Goa KL, Balfour JA, Zuanetti G. Lisinopril. A review of its pharmacology and clinical efficacy in the early management of acute myocardial infarction. Drugs. 1996 Oct;52(4):564-88. PMID: 8891468.

Apostolakis S, Krambovitis E, Vlata Z, et al. CX3CR1 receptor is up-regulated in monocytes of coronary artery diseased patients: impact of pre-inflammatory stimuli and renin-angiotensin system modulators. Thromb Res. 2007;121(3):387-395. PMID: 17521710.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Email
This field is for validation purposes and should be left unchanged.

Lisinopril Dihydrate

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

VS-4718

Abacavir Sulfate

BGB-283

Epothilone B

Ofloxacin

Mastoparan 7

Sutezolid

Naltriben

PF-06873600

Entinostat

Recombinant TpN 17 protein

Oseltamivir Phosphate

Rasagiline Mesylate

IC261

Kahweol Acetate

AS-605240

Ac-DEVD-pNA

γ-Tocopherol

5-Methoxyindole

Indirubin

Footer