LKT Labs

Biochemicals for Life Science Research

Medroxyprogesterone 17-Acetate

Medroxyprogesterone 17-Acetate

Product ID M1613
Cas No. 71-58-9
Purity ≥99%
Product Unit SizeCostQuantityStock
500 mg $78.00 In stock
1 g $130.00 In stock
5 g $499.00 In stock
Bulk Quote

Quicklinks

Description

Medroxyprogesterone 17-acetate (MPA) is a synthetic steroid that activates progesterone, androgen, and glucocorticoid receptors. MPA exhibits contraceptive and anticancer activities and is also used in hormone replacement therapy, endometriosis, and dysmenorrhea. MPA decreases levels of adrenocorticotropic hormone (ACTH), cortisol, and other hormones; it also inhibits 3α-hydroxysteroid dehydrogenase. This compound is used clinically to treat breast cancer and inhibits the proliferation and growth of breast cancer cells and tumors in various models.

Product Info

Cas No.

71-58-9
Purity

≥99%
Formula

C24H34O4
Formula Wt.

386.52
Chemical Name

17-α-Acetoxy-6α-methylprogesterone
IUPAC Name

[(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,6,7,8,9, 11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
Synonym

MAP, Clinovir, Depo-Provera, Farlutal, Nidaxin, Oragest, Prodasone, Provera, Veramix
Melting Point

207-209°C
Solubility

Soluble in chloroform or acetone.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

M1613 MSDS PDF
Info Sheet

M1613 Info Sheet PDF

References

Schindler AE, Campagnoli C, Druckmann R, et al. Classification and pharmacology of progestins. Maturitas. 2008 Sep-Oct;61(1-2):171-80. PMID: 19434889.

Meyer L, Venard C, Schaeffer V, et al. The biological activity of 3alpha-hydroxysteroid oxido-reductase in the spinal cord regulates thermal and mechanical pain thresholds after sciatic nerve injury. Neurobiol Dis. 2008 Apr;30(1):30-41. PMID: 18291663.

Poulin R, Baker D, Poirier D, et al. Androgen and glucocorticoid receptor-mediated inhibition of cell proliferation by medroxyprogesterone acetate in ZR-75-1 human breast cancer cells. Breast Cancer Res Treat. 1989 Mar;13(2):161-72. PMID: 2525057.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C4557

    Clofibrate

    Fibrate; PPARα agonist.

    ≥99%
  • D3431

    3,4-Dihydroxyphenyl Ethanol

    Polyphenol found in olive oil, antioxidant.

    ≥95%
  • A4802

    Amantadine Hydrochloride

    Viral M2 proton channel blocker, MAO-A, NET, NM...

    ≥98%
  • O610292

    Ophiobolin B

    Naturally occurring sesteterpenoid.

    ≥98%
  • J5237

    JNJ-26854165

    MDM2 inhibitor.

    ≥98%
  • M568268

    Mogroside IV

    Triterpenoid

    ≥98%
  • A744789

    ASTX660

    Antitumor

    ≥98%
  • G4797

    GLYX-13 Trifluoroacetate

    Peptide; NMDA partial agonist.

    ≥98%
  • D8014

    DU-14

    Steroid sulfatase inhibitor.

    ≥98%
  • D0808

    DCC-2036

    Abl inhibitor.

    ≥98%
  • P7058

    Protocatechuic Aldehyde

    Polyphenol found in various plants and foods.

    ≥98%
  • S4932

    SMI-4a

    Thiazolidine; Pim kinase inhibitor.

    ≥99%
  • O4532

    Oligomycin B

    Macrolide; F1F0 ATP synthase inhibitor.

    ≥97%, TLC, HPLC
  • E5241

    Met-Enkephalin

    Endogenous opioid peptide; δOR and μOR agonis...

    ≥95%
  • A0816

    Acemetacin

    Glycolic acid ester prodrug of indomethacin, NS...

    ≥98%
  • M1564

    S-Methyl-L-cysteine

    Antioxidant found in Brassicaceae family plants...

    ≥99%
  • K0023

    K252c

    Staurosporine analog; PKC and PKA inhibitor.

    ≥98%
  • P8117

    Puerarin, High Purity

    Isoflavone found in Pueraria; 5-HT2C and GABA-A...

    ≥99%
  • K7600

    KT5720

    PKA and PDK1 inhibitor, HCN channel blocker, po...

    ≥98%
  • F1655

    Fenoprofen Calcium Dihydrate

    NSAID; COX-1/2 inhibitor.

    ≥97%