• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Ofloxacin

Ofloxacin

Product ID O2144
Cas No. 82419-36-1
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $75.10 In stock
10 g $135.10 In stock
50 g $525.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ofloxacin is a second generation fluoroquinolone antibiotic. This compound is often given as a topical treatment for ocular and otic infections. Like other fluoroquinolones, ofloxacin inhibits DNA gyrase and topoisomerase IV; it exhibits antibacterial efficacy against both gram positive and gram negative bacteria. Under UV light, ofloxacin exhibits phototoxicity, disputing the mitochondrial membrane potential and inducing ROS-mediated DNA damage.

Product Info

Cas No.

82419-36-1

Purity

≥98%

Formula

C18H20FN3O4

Formula Wt.

361.37

Chemical Name

7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3- dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo- , (+-)-

IUPAC Name

7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

Synonym

Floxin, Ofloxacin,Tarivid

Melting Point

250-257°C (dec.)

Solubility

Slightly soluble in water, DMSO, methanol, chloroform. Soluble in 1M NaOH (50 mg/mL).

Appearance

Off White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

O2144 MSDS PDF

Info Sheet

O2144 Info Sheet PDF

References

Dwivedi A, Mujtaba SF, Yadav N, et al. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radic Res. 2014 Mar;48(3):333-46. PMID: 24286391.

Pantel A, Petrella S, Matrat S, et al. DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011 Oct;55(10):4524-9. PMID: 21768507.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T3454

    Tinidazole

    Nitroimidazole, binds DNA; nucleic acid synthes...

    ≥98%
  • L1684

    Levonorgestrel

    Synthetic progestogen; contraceptive.

    ≥98%
  • O4400

    Olanzapine

    AMPK activator, D1-4, 5-HT1A/2/3/6/7, M1-5 mACh...

    ≥99%
  • D0025

    DAMGO

    Synthetic peptice; μOR agonist.

    ≥95%
  • C2816

    Cheirolin

    Naturally produced ITC, sulfonyl analog of sulf...

    ≥97%
  • R1217

    RDEA119

    MEK1/2 inhibitor.

    ≥98%
  • D3447

    Diltiazem Hydrochloride

    Benzothiazepine; L-type Ca2+ channel blocker, p...

    ≥98%
  • D004098

    Dacomitinib Anhydrous

    EGFR inhibitor.

    ≥99%
  • J0001

    J-147

    Phenyl hydrazide; neuronal oxidative stress inh...

    ≥98%
  • T1670

    Terazosin Hydrochloride Dihydrate

    Quinazoline; α1-adrenergic antagonist.

    ≥98%
  • T3585

    Tivozanib

    VEGFR1/2/3, c-Kit, PDGFR inhibitor.

    ≥98%
  • S8253

    Sunitinib Malate

    Indoline; PDGFR, VEGFR, c-KIT, FLT3, mTORC1 inh...

    ≥98%
  • B1898

    Bezafibrate

    Fibrate; PPARα agonist.

    ≥98%
  • C9673

    Cysteamine Hydrochloride

    Aminothiol, CoA component; ulcer inducer.

    ≥99%
  • P2002

    PF-04691502 Dihydrate

    PI3K and mTOR inhibitor.

    ≥98%
  • S8047

    R,S-Sulforaphane, Research Grade

    Synthetic ITC.

    ≥97%
  • S0254

    Sanguinarine Chloride

    Decreases expression of MMPs, PGE2, and COX-2, ...

    ≥98%
  • E5221

    Endothelin-2, human

    Endogenous peptide involved in vascular contrac...

    ≥95%
  • G7232

    GS-9973

    Syk inhibitor.

    ≥98%
  • E537335

    Enniatin B1

    Mycotoxin contaminant found in cereal grains.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only