• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Ofloxacin

Ofloxacin

Product ID O2144
Cas No. 82419-36-1
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $75.10 In stock
10 g $135.10 In stock
50 g $525.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ofloxacin is a second generation fluoroquinolone antibiotic. This compound is often given as a topical treatment for ocular and otic infections. Like other fluoroquinolones, ofloxacin inhibits DNA gyrase and topoisomerase IV; it exhibits antibacterial efficacy against both gram positive and gram negative bacteria. Under UV light, ofloxacin exhibits phototoxicity, disputing the mitochondrial membrane potential and inducing ROS-mediated DNA damage.

Product Info

Cas No.

82419-36-1

Purity

≥98%

Formula

C18H20FN3O4

Formula Wt.

361.37

Chemical Name

7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3- dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo- , (+-)-

IUPAC Name

7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

Synonym

Floxin, Ofloxacin,Tarivid

Melting Point

250-257°C (dec.)

Solubility

Slightly soluble in water, DMSO, methanol, chloroform. Soluble in 1M NaOH (50 mg/mL).

Appearance

Off White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

O2144 MSDS PDF

Info Sheet

O2144 Info Sheet PDF

References

Dwivedi A, Mujtaba SF, Yadav N, et al. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radic Res. 2014 Mar;48(3):333-46. PMID: 24286391.

Pantel A, Petrella S, Matrat S, et al. DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011 Oct;55(10):4524-9. PMID: 21768507.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B8363

    Bupropion Hydrochloride

    α3β2, α3β4, α4β2 nAChR antagonist, indire...

    ≥98%
  • A5039

    Amitraz

    Insecticide; α-adrenergic agonist, MAO inhibit...

    ≥97%
  • T5944

    Tolmetin Sodium

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • P3561

    Piperlongumine

    Found in Piper longum; TxA2 antagonist, ubiquit...

    ≥98%
  • T9974

    [Asp371]-Tyrosinase (369-377), human

    Proteasome antigen.

    ≥95%
  • B5874

    Bosutinib

    Src and Abl inhibitor.

    ≥98%
  • E5211

    Endomorphin-2

    Endogenous opioid peptide; μOR agonist.

    ≥95%
  • C3263

    Ciprofloxacin Hydrochloride Monohydrate

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • B1668

    Berteroin

    Thio sulforaphane analog, ITC.

    ≥97%
  • A761003

    AT-7519 Hydrochloride

    ATP competitive CDK inhibitor.

    ≥98%
  • V182685

    Verdinexor

    CRM1/XPO1 inhibitor.

    ≥99%
  • C9608

    Cycloastragenol

    Triterpene aglycone found in Radix Astragali; t...

    ≥98%
  • T7044

    Triamcinolone Acetonide Acetate

    Steroid; glucocorticoid agonist.

    ≥97%
  • H0002

    H8 dihydrochloride

    PKA inhibitor.

    ≥98%
  • J766160

    JTE907

    Selective Cannabinoid receptor 2(CB2) inverse a...

    ≥98%
  • C0175

    Carbetocin Acetate

    Peptide, oxytocin analog; potential OXTR agonis...

    ≥95%
  • A5472

    Ansamitocin P3

    Microtubule depolymerization inhibitor.

    ≥70% (P3), Total Ansamitocins ≥95%
  • L0248

    Laminin Peptide YIGSR

    Laminin-derived peptapeptide.

    ≥98%
  • W0247

    Walrycin B

    Walrycin response regulator inhibitor.

    ≥98%
  • P6954

    Pioglitazone Hydrochloride

    Thiazolidinedione; PPARα/γ agonist, mitoNEET ...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only