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Peptide YY, human

Peptide YY, human

Product ID P1763
Cas No. 118997-30-1
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $420.00 Please Inquire
2 mg $735.00 Please Inquire
5 mg $1,260.00 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
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Description

Peptide YY is an endogenous neuropeptide Y-related peptide that activates Y1 and Y2 receptors. Peptide YY is an appetite-regulating hormone secreted from the gastrointestinal tract that exhibits anorexigenic and gastrointestinal motility modulating activities. Peptide YY decreases osteoblast activity, contributing to bone loss in clinical settings in which patients have recently lost weight. Peptide YY also decreases levels of AMPK and phosphorylated acetyl CoA carboxylase in the liver, decreasing lipid oxidation and/or increasing lipogenesis. Peptide YY also induces slight improvements in insulin response during glucose challenge in animal models. In other in vivo models, peptide YY induces mucosal anti-secretory activity, inhibiting colonic and upper gastrointestinal transit.

Product Info

Cas No.

118997-30-1

Purity

≥98%

Formula

C194H295N55O57

Formula Wt.

4309.8

Synonym

Peptide tyrosine tyrosine, PYY

Solubility

Soluble in water, acid.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

P1763 MSDS PDF

Info Sheet

P1763 Info Sheet PDF

References

Wong IP, Driessler F, Khor EC, et al. Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology. PLoS One. 2012;7(7):e40038. PMID: 22792209.

Shi YC, Hämmerle CM, Lee IC, et al. Adult-onset PYY overexpression in mice reduces food intake and increases lipogenic capacity. Neuropeptides. 2012 Aug;46(4):173-82. PMID: 22575886.

Tough IR, Forbes S, Tolhurst R, et al. Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit differentially via Y1 and Y2 receptors. Br J Pharmacol. 2011 Sep;164(2b):471-84. PMID: 21457230.

Custom Order

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