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Pidotimod

Pidotimod

Product ID P3313
Cas No. 121808-62-6
Purity ≥98%
Product Unit SizeCostQuantityStock
250 mg $67.80 In stock
1 g $112.60 In stock
5 g $225.40 In stock
10 g $375.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Pidotimod is an immunostimulatory compound often used as an adjuvant. Pidotimod is clinically used to treat acute respiratory tract infections and stimulates both cellular and humoral immunity. In animal models of Toxoplasma infection, pidotimod increases levels of Th1 cytokines and decreases parasite burden, improving survival rates, survival times, and liver histopathology. Pidotimod also promotes maturation of dendritic cells, upregulating expression of CD83 and CD86.

Product Info

Cas No.

121808-62-6

Purity

≥98%

Formula

C9H12N2O4S

Formula Wt.

244.27

Chemical Name

(R)-3-((S)-5-Oxoprolyl)-4-thiazolidinecarboxylic acid

IUPAC Name

(4R)-3-[(2S)-5-oxopyrrolidine-2-carbonyl]-1,3-thiazolidine-4-carboxylic acid

Synonym

Axil, Onaka, Pigitil, Polimod

Melting Point

194-198°C

Solubility

Soluble in water (37.8 g/L), methanol (13.8 g/L), ethanol (4.4 g/L), and DMF (72.4g/L).

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P3313 MSDS PDF

Info Sheet

P3313 Info Sheet PDF

References

Zuccotti GV, Mameli C. Pidotimod: the past and the present. Ital J Pediatr. 2013 Dec 6;39:75. PMID: 24314100.

Zhao Y, Huang B, Huang S, et al. Evaluation of the adjuvant effect of pidotimod on the immune protection induced by UV-attenuated Toxoplasma gondii in mouse models. Parasitol Res. 2013 Sep;112(9):3151-60. PMID: 23783399.

Giagulli C, Noerder M, Avolio M, et al. Pidotimod promotes functional maturation of dendritic cells and displays adjuvant properties at the nasal mucosa level. Int Immunopharmacol. 2009 Nov;9(12):1366-73. PMID: 19712757.

Custom Order

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