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Vesicular stomatitis virus (VSV) is an antigenic peptide fragment of VSV that binds the LDL receptor. VSV exhibits anticancer chemotherapeutic potential. VSV is used as a vector to express tumor-targeting ligands, allowing the virus to target, infect, and kill tumor cells. VSV inhibits myeloma growth in vivo and also kills a variety of neuroendocrine cells in vitro and in vivo.
| Cas No. | 132326-74-0 |
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| Purity | ≥95% |
| Formula | C44H66N12O12 |
| Formula Wt. | 955.09 |
| Synonym | Veiscular Stomatitis Virus NP(52-59), VSV-8 |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Ammayappan A, Peng KW, Russell SJ. Characteristics of oncolytic vesicular stomatitis virus displaying tumor-targeting ligands. J Virol. 2013 Dec;87(24):13543-55. PMID: 24089573.
Randle RW, Northrup SA, Sirintrapun SJ, et al. Oncolytic vesicular stomatitis virus as a treatment for neuroendocrine tumors. Surgery. 2013 Dec;154(6):1323-29; discussion 1329-30. PMID: 23973113.
Naik S, Nace R, Barber GN, et al. Potent systemic therapy of multiple myeloma utilizing oncolytic vesicular stomatitis virus coding for interferon-β. Cancer Gene Ther. 2012 Jul;19(7):443-50. PMID: 22522623.