Description
This compound is a benzyl analog of taxol. Like other taxanes, this compound may also promote microtubule polymerization and prevent microtubule depolymerization, exhibiting anticancer activity.
Product Unit Size | Cost | Quantity | Stock |
---|
This compound is a benzyl analog of taxol. Like other taxanes, this compound may also promote microtubule polymerization and prevent microtubule depolymerization, exhibiting anticancer activity.
Cas No. | 173101-56-9 |
---|---|
Purity | ≥95% |
Formula | C48H53NO14 |
Formula Wt. | 867.93 |
IUPAC Name | [4,12-diacetyloxy-1,9-dihydroxy-15-[2-hydroxy-3-phenyl-3-[(2-phenylacetyl)amino]propanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
Synonym | Taxol F; Paclitaxel impurity P; |
Appearance | White to off white powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.
Orr GA, Verdier-Pinard P, McDaid H, et al. Mechanisms of Taxol resistance related to microtubules. Oncogene. 2003 Oct 20;22(47):7280-95. PMID: 14576838.
Jordan MA. Mechanism of action of antitumor drugs that interact with microtubules and tubulin. Curr Med Chem Anticancer Agents. 2002 Jan;2(1):1-17. PMID: 12678749.
NDRI inhibitor
Inhibitor of VEGFR and FGFR.
Naturally occuring isothiocyanate found in broc...
B-Raf, VEGFR2, c-Raf, PDGFR, CSF-1R, RET, c-Kit...
Peptide, confers resistance against macrolide a...
Fermentation impurity
NSAID; COX-1/2 and PDE inhibitor.
Chloramphenicol derivative; protein translation...
GRP analog, found in Bombina; bombesin and GRP ...
Trichothecene mycotoxin produced by Fusarium; p...
Polyketide; CRM1 inhibitor.
AChE inhibitor, F0F1-ATP synthase modulator.
Lck, Src, SIK inhibitor.
Neurotoxin, mutagen.
5-HT1A agonist, D2, 5-HT1D antagonist.
Cysteine-ITC conjugate, BITC derivative, antiox...
HDAC inhibitor.
MEK1/2 and ERK inhibitor.
Semi-synthetic avermectin; GABA potentiator.
Macrolide; protein synthesis inhibitor.