Description
2’-Acetyltaxol is an intermediate in taxane synthesis that appears to have minimal effects on microtubule polymerization, although current research is limited.
| Product Unit Size | Cost | Quantity | Stock |
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2’-Acetyltaxol is an intermediate in taxane synthesis that appears to have minimal effects on microtubule polymerization, although current research is limited.
| Cas No. | 92950-40-8 |
|---|---|
| Purity | ≥98% |
| Formula | C49H53NO15 |
| Formula Wt. | 895.95 |
| Chemical Name | Benzenepropanoic acid, α-(acetyloxy)-β- (benzoyl- amino)-,6,12b-bis(acetyloxy)-12-(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11- dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR) |
| IUPAC Name | [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-2-acetyloxy-3-benzamido-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
| Synonym | Taxol 2'-acetate, 2’-acetyl taxol |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Williams HJ, Moyna G, Scott AI, et al. NMR and molecular modeling study of the conformations of taxol 2'-acetate in chloroform and aqueous dimethyl sulfoxide solutions. J Med Chem. 1996 Mar 29;39(7):1555-9. PMID: 8691488.
Mellado W, Magri NF, Kingston DG, et al. Preparation and biological activity of taxol acetates. Biochem Biophys Res Commun. 1984 Oct 30;124(2):329-36. PMID: 6548627.
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