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Boc-FLFLF is an antagonist at the formyl peptide receptor-like 1 receptor (FPR1). This peptide increases pain effects and inhibits antinociceptive activity of annexin. Box-FLFLF also inhibits muscle contractions induced by formyl peptides.
| Cas No. | 148182-34-7 |
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| Purity | ≥95% |
| Formula | C44H59N5O8 |
| Formula Wt. | 785.99 |
| IUPAC Name | (2S)-2-[[(2S)-4-methyl-2-[[(2S)-2-[[(2S)-4-methyl-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acid |
| Synonym | L-Phenylalanine, N-(N-(N-(N-(N-((1,1- dimethylethoxy)carbonyl)-D-phenylalanyl)-L-leucyl)-D- phenylalanyl)-L-leucyl)- |
| Solubility | Soluble in DMSO. |
| Appearance | White to off white powder |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Pei L, Zhang J, Zhao F, et al. Annexin 1 exerts anti-nociceptive effects after peripheral inflammatory pain through formyl-peptide-receptor-like 1 in rat dorsal root ganglion. Br J Anaesth. 2011 Dec;107(6):948-58. PMID: 21990306.
Ma XJ, Kunimatsu M, Ozaki Y, et al. Putative mechanism for guinea pig ileum contraction by N-formyl peptides. A comparative study of N-formyl and N-acetyl peptides with the N-terminal sequence of the calpain small subunit. Life Sci. 1995;57(5):463-71. PMID: 7623613.