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Ciprofloxacin Hydrochloride Monohydrate

Ciprofloxacin Hydrochloride Monohydrate

Product ID C3263
Cas No. 86393-32-0
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $56.90 In stock
25 g $157.50 In stock
50 g $268.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ciprofloxacin is a second generation fluoroquinolone antibiotic that exhibits antibacterial activity against both gram negative and gram positive bacteria. Ciprofloxacin inhibits DNA gyrase and topoisomerase IV, preventing DNA replication.

Product Info

Cas No.

86393-32-0

Purity

≥98%

Formula

C17H18FN3O3 • HCl • H2O

Formula Wt.

385.82

Chemical Name

1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3- quinolinecarboxylic acid monohydrochloride

IUPAC Name

1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;hydrate;hydrochloride

Synonym

CiproR, Ciflan, Floxacipron, Proxacin

Melting Point

314-324°C

Solubility

Soluble in water (3.5 g/100 ml), ethanol (1.6 mg/ml). Reconstitute with suitable solvent. Aliquot and store at -20°C. Solutions should be protected from light. Reconstituted product is stable for 6 months at -20°C.

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

C3263 MSDS PDF

Info Sheet

C3263 Info Sheet PDF

References

Rajendram M, Hurley KA, Foss MH, et al. Gyramides Prevent Bacterial Growth by Inhibiting DNA Gyrase and Altering Chromosome Topology. ACS Chem Biol. 2014 Apr 22. [Epub ahead of print]. PMID: 24712739.

Oliphant CM, Green GM. Quinolones: a comprehensive review. Am Fam Physician. 2002 Feb 1;65(3):455-64. PMID: 11858629.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

Aldred KJ, McPherson SA, Wang P, et al. Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance. Biochemistry. 2012 Jan 10;51(1):370-381. PMID: 22126453.

Custom Order

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