• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Diclofenac Chloroacetyl impurity

Diclofenac Chloroacetyl impurity

Product ID D324104
Cas No. 15308-01-7
Purity ≥99%
Product Unit SizeCostQuantityStock
100 mg $114.20 In stock
500 mg $300.40 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Diclofenac Chloroacetyl impurity is an impurity of Diclofenac.

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that is clinically used to treat inflammation associated with arthritis and gout as well as other pain or inflammatory disorders; it is somewhat selective in inhibiting COX-2 over COX-1. Diclofenac exhibits anti-inflammatory, antipyretic, analgesic, antinociceptive, anticonvulsant, anti-angiogenic, anticancer chemotherapeutic, and chemopreventive activities. In vitro, the anticonvulsant/antiepileptic activity of diclofenac may stem from inhibition of delayed rectifier K+ channel amplitude and acceleration of channel inactivation; it also increases the amplitude of M-type K+ channels. This compound inhibits DMH-induced colon carcinogenesis in vivo, decreasing levels of COX-2, VEGF, and MCP-1. Diclofenac also decreases the epithelial-to-mesenchymal transition (EMT), suppressing squamous cell carcinoma tumor growth.

Product Info

Cas No.

15308-01-7

Purity

≥99%

Formula

C14H10Cl3NO

Formula Wt.

314.59

Chemical Name

2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide

IUPAC Name

2-chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide

Synonym

Acetamide, 2-chloro-N-(2,6-dichlorophenyl)-N-phenyl-, ZA3DY2Z4ZR, Diclofenac Related Compound (N-Chloroacetyl-N-phenyl-2,6-dichloroaniline); Diclofenac impurity 5.

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

D324104 MSDS PDF

Info Sheet

D324104 Info Sheet PDF

References

Arumugam A, Weng Z, Talwelkar SS, et al. Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis. PLoS One. 2013 Nov 8;8(11):e80076. PMID: 24260338.

Akbari E, Mirzaei E, Shahabi Majd N. Long-term Morphine-treated Rats are more Sensitive to Antinociceptive Effect of Diclofenac than the Morphine-naive rats. Iran J Pharm Res. 2013 Winter;12(1):175-84. PMID: 24250586.

Huang CW, Hung TY, Liao YK, et al. Underlying mechanism of regulatory actions of diclofenac, a nonsteroidal anti-inflammatory agent, on neuronal potassium channels and firing: an experimental and theoretical study. J Physiol Pharmacol. 2013 Jun;64(3):269-80. PMID: 23959723.

Kaur J, Sanyal SN. Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1α and VEGF. Mol Carcinog. 2011 Sep;50(9):707-18. PMID: 21268133.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • W4096

    WKYMVM-NH2

    Synthetic peptide; FPRL1 agonist.

    ≥95%
  • A5044

    Amlodipine Besylate

    Dihydropyridine, FIASMA; L-type Ca2+ channel bl...

    ≥98%
  • T0140

    TAK-632

    RAF inhibitor.

    ≥99%
  • T0003

    T2 Tetraol

    Trichothecene mycotoxin produced by Fusarium.

    ≥97%, TLC
  • O6932

    Oridonin

    Diterpenoid found in Rabdosia rubescens; potent...

    ≥98%
  • L5624

    Loganin

    Iridoid glucoside found in Cornus officialis; Î...

    ≥98%
  • R7680

    Recombinant M. Tuberculosis Antigen TB 38+6+10

    Tuberculosis antigen

  • A0902

    N-Acetyl-S-(N′-phenylhexylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate, antioxidant; HDAC inhib...

    ≥98%
  • A4940

    6-Aminonicotinamide

    G6PDH inhibitor.

    ≥98%
  • C0027

    Cafestol Linoleate

    Diterpene found in brewed, unfiltered coffee; F...

    ≥98%
  • P9870

    Pyridostatin Hydrochloride

    G-quadruplex ligand; DNA breakage inducer.

    ≥97%
  • T1670

    Terazosin Hydrochloride Dihydrate

    Quinazoline; α1-adrenergic antagonist.

    ≥98%
  • B8074

    3-tert-Butyl-5-Methoxy-1,2-quinone

    BHA derivative.

    ≥98%
  • D3200

    Diacetoxyscirpenol

    Type A trichothecene mycotoxin produced by Fusa...

    ≥98%
  • P5878

    Potassium Canrenoate

    Aldosterone antagonist.

    ≥98%
  • C6957

    Croton Oil

    Mixture found in Croton, used to induce inflamm...

  • S8345

    S-(−)-Sulpiride

    GHB agonist, D2/3 antagonist.

    ≥99%
  • A5132

    Amikacin Disulfate

    Aminoglycoside; protein translation inhibitor.<...

    ≥98%
  • H2980

    Humanin, human

    Endogenous peptide; FPRL1/2 agonist.

    ≥95%
  • G4484

    Glucagon-like Peptide II, rat

    Endogenous peptide hormone, involved in intesti...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only