• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Peimine

Peimine

Product ID P1634
Cas No. 23496-41-5
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $102.00 In stock
10 mg $163.40 In stock
25 mg $302.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Peimine is a steroidal alkaloid found in a variety of species of the Fritillaria plant; it exhibits anti-inflammatory activity and acts as an expectorant and anti-tussive in cough medications. Peimine’s anti-tussive activity may result from negative potentiation of transient receptor potential channels TRPV1 and TRPA1 in vitro. Peimine inhibits cough frequency and cough latency in animal models. Additionally, peimine binds the DNA duplex, inhibits production of pro-inflammatory cytokines like TNF-α, IL-6, and IL-1β, and decreases expression of IκB kinase, JNK, and p38.

Product Info

Cas No.

23496-41-5

Purity

≥98%

Formula

C27H45NO3

Formula Wt.

431.65

Chemical Name

(1R,2S,6S,9S,10S,11S,14S,15S,17S,18S,20S,23R,24S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-10,17,20-triol

IUPAC Name

(1R,2S,6S,9S,10S,11S,14S,15S,17S,18S,20S,23R,24S)-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-10,17,20-triol

Synonym

Verticine, Wanpeinine A

Appearance

White Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P1634 MSDS PDF

Info Sheet

P1634 Info Sheet PDF

References

Yi PF, Wu YC, Dong HB, et al. Peimine impairs pro-inflammatory cytokine secretion through the inhibition of the activation of NF-κB and MAPK in LPS-induced RAW264.7 macrophages. Immunopharmacol Immunotoxicol. 2013 Oct;35(5):567-72. PMID: 23944357.

Ma L, Song F, Liu Z, et al. Study on noncovalent complexes of alkaloids with DNA duplex using electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom. 2013 Jan 15;27(1):51-8. PMID: 23239316.

Wang D, Zhu J, Wang S, et al. Antitussive, expectorant and anti-inflammatory alkaloids from Bulbus Fritillariae Cirrhosae. Fitoterapia. 2011 Dec;82(8):1290-4. PMID: 21958967.

Zhang Y, Sreekrishna K, Lin Y, et al. Modulation of transient receptor potential (TRP) channels by Chinese herbal extracts. Phytother Res. 2011 Nov;25(11):1666-70. PMID: 21432926.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A5219

    Anethole Trithione

    Oltipraz analog, salivary gland secretion enhan...

    ≥98%
  • E4418

    β-Elemene

    Sesquiterpene found in various plant sources. <...

    ≥98%
  • C4532

    Clindamycin Hydrochloride

    Lincosamide; ribosomal translocation and protei...

    ≥98%
  • G0247

    2″O-Galloylhyperin

    Flavonoid glycoside found in Pyrola.

    ≥98%
  • M1444

    MDL 29951

    GPR17 agonist, NMDA and fructose 1,6-bisphospha...

    ≥98%
  • T6834

    Triacsin C

    Acyl-CoA synthetase inhibitor.

    ≥95%
  • R4132

    RKI-1447

    ROCK1/2 inhibitor.

    ≥98%
  • M1335

    Mdivi-1

    Quinazolinone; mitochondrial division inhibitor...

    ≥98%
  • C864760

    CVT-313

    Selective CDK2 inhibitor.

    ≥98%
  • M7528

    α-Melanocyte Stimulating Hormone

    Endogenous peptide hormone derived from POMC, i...

    ≥98%
  • S0048

    Salicin

    Alcoholic β-glucoside found in willow bark, sa...

    ≥98%
  • D760022

    DT-2216

    BCL-XL specific degrader

    ≥98%
  • A4498

    Alytesin

    Antimicrobial peptide found in amphibians.

    ≥95%
  • C0044

    CAL101

    p110δ PI3K inhibitor.

    ≥99%
  • R0249

    Ramipril

    ACE inhibitor.

    ≥98%
  • K0022

    K252b

    Staurosporine analog; PKC inhibitor.

    ≥98%
  • A480010

    AM630

    CB2 receptor antagonist.

    ≥97%
  • S7870

    Streptozocin

    Nitrosourea-amino sugar conjugate, DNA cross-li...

    ≥98%
  • W5769

    Wortmannin

    Steroid produced by Penicillum; PI3K, mTOR, DNA...

    ≥97%
  • B6918

    Brevetoxin 3

    Polyether neurotoxin found in Karenia brevis; N...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only