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α-Conotoxin GI

α-Conotoxin GI

Product ID C5655
Cas No. 76862-65-2
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $102.90 In stock
1 mg $173.30 In stock
2.5 mg $341.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

α-Conotoxin GI is a peptide inhibitor of nicotinic acetylcholine receptors (nAChRs) originally found in species of Conus snails. α-Conotoxin GI binds nAChRs at αγ and αδ interfaces. α-Conotoxin GI decreases peak amplitude and induces tetanic and train-of-four fades, modulating acetylcholine signaling at the neuromuscular junction.

Product Info

Cas No.

76862-65-2

Purity

≥95%

Formula

C55H80N20O18S4

Formula Wt.

1437.61

Solubility

Soluble in water, PBS.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C5655 MSDS PDF

Info Sheet

C5655 Info Sheet PDF

References

Hann RM, Pagán OR, Gregory LM, et al. The 9-arginine residue of alpha-conotoxin GI is responsible for its selective high affinity for the alphagamma agonist site on the electric organ acetylcholine receptor. Biochemistry. 1997 Jul 22;36(29):9051-6. PMID: 9220994.

Blount K, Johnson A, Prior C, et al. alpha-Conotoxin GI produces tetanic fade at the rat neuromuscular junction. Toxicon. 1992 Aug;30(8):835-42. PMID: 1355934.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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