• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Astilbin

Astilbin

Product ID A7577
Cas No. 29838-67-3
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $112.20 In stock
10 mg $173.70 In stock
25 mg $306.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Astilbin is a flavonoid found in several plants, including species of Engelhardia and Smilax. Astilbin displays anticancer, antioxidative, anti-inflammatory, and immunosuppressive activities. In vitro, astilbin inhibits expression of IL-1β, IL-6, IL-10, MCP-1, and TNF-α, as well as activity of horseradish peroxidase and myeloperoxidase. This compound also inhibits maturation of and antigen presentation by dendritic cells and activation and proliferation of T cells. Astilbin downregulates NF-κB and c-Myc and induces cell cycle arrest and caspase-mediated apoptosis in hepatoma cells. Additionally, astilbin also inhibits release of prostaglandin E2.

Product Info

Cas No.

29838-67-3

Purity

≥99%

Formula

C21H22O11

Formula Wt.

450.39

Chemical Name

5,7,3',4'-tetrahydroxy-2,3-dihydroflavonol-3-ß-o-rhamnoside

IUPAC Name

(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4, 5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one

Synonym

Astibin, Isoastilbin, Taxifolin 3-O-rhamnoside, Neoisoastilbin

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A7577 MSDS PDF

Info Sheet

A7577 Info Sheet PDF

References

Li P, Gao S, Jie W, et al. Astilbin inhibits proliferation of rat aortic smooth muscle cells induced by angiotensin II and down-regulates expression of protooncogene. J Huazhong Univ Sci Technolog Med Sci. 2012 Apr;32(2):181-5. PMID: 22528217.

Huang H, Cheng Z, Shi H, et al. Isolation and characterization of two flavonoids, engeletin and astilbin, from the leaves of Engelhardia roxburghiana and their potential anti-inflammatory properties. J Agric Food Chem. 2011 May 11;59(9):4562-9. PMID: 21476602.

Petacci F, Freitas SS, Brunetti IL, et al. Inhibition of peroxidase activity and scavenging of reactive oxygen species by astilbin isolated from Dimorphandra mollis (Fabaceae, Caesalpinioideae). Biol Res. 2010;43(1):63-74. PMID: 21157633.

Zou S, Shen X, Tang Y, et al. Astilbin suppresses acute heart allograft rejection by inhibiting maturation and function of dendritic cells in mice. Transplant Proc. 2010 Nov;42(9):3798-802. PMID: 21094859.

Lucas-Filho MD, Silva GC, Cortes SF, et al. ACE inhibition by astilbin isolated from Erythroxylum gonocladum (Mart.) O.E. Schulz. Phytomedicine. 2010 Apr;17(5):383-7. PMID: 19879122.

Sa F, Gao JL, Fung KP, et al. Anti-proliferative and pro-apoptotic effect of Smilax glabra Roxb. extract on hepatoma cell lines. Chem Biol Interact. 2008 Jan 10;171(1):1-14. PMID: 17996228.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • J5237

    JNJ-26854165

    MDM2 inhibitor.

    ≥98%
  • A4441

    Allicin, aqueous solution

    Organosulfur found in garlic; Kir K+ channel ac...

    ≥98%
  • D3203

    Diallyl Tetrasulfide

    Organosulfur found in garlic; Microtubule polym...

    ≥90%
  • G3351

    Ginkgolic Acid (17:1)

    Mixture of alkylphenols found in Ginkgo; HIV pr...

    ≥98%
  • V1871

    Veratridine

    Binds to neurotoxin receptor site 2 on voltage-gat...
    ≥98%
  • C577524

    Concanamycin A

    Macrolide lactone antibiotic.

    ≥98%
  • L5648

    Lomustine

    Nitrosourea, DNA alkylator.

    ≥98%
  • H1695

    S-Hexylglutathione

    Glutathione-S-transferase inhibitor.

    ≥98%
  • O2146

    R-(+)-Ofloxacin

    Fluoroquinolone, optically active isomer of ofl...

    ≥98%
  • D0169

    Darifenacin Hydrobromide

    M3 mAChR antagonist.

    ≥98%
  • P0244

    Palbociclib Hydrochloride

    CDK4/6 inhibitor.

    ≥99%
  • V5886

    Voriconazole

    Triazole; 14α demethylase inhibitor.

    ≥98%
  • D0363

    Daptomycin

    Anionic lipopeptide, alters cell membrane organ...

    ≥97%
  • F1670

    Ferulic Acid Methyl Ester

    Hydroxycinnamic aicd, verbascoside metabolite, ...

    ≥98%
  • C0273

    Casin

    Cdc42 GTPase inhibitor.

    ≥97%
  • T3461

    Tiplaxtinin

    PAI-1 inhibitor.

    ≥98%
  • C8069

    Curcumin

    Diarylheptanoid found in Zingiberaceae.

    ≥97% curcuminoid content
  • I088240

    (S,S)-ICG-001

    Wnt/β-catenin inhibitor

    ≥98%
  • V1810

    Vecuronium Bromide

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%
  • T0153

    Tanshinone I

    Diterpene found in Salvia.

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only