• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Astilbin

Astilbin

Product ID A7577
Cas No. 29838-67-3
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $112.20 In stock
10 mg $173.70 In stock
25 mg $306.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Astilbin is a flavonoid found in several plants, including species of Engelhardia and Smilax. Astilbin displays anticancer, antioxidative, anti-inflammatory, and immunosuppressive activities. In vitro, astilbin inhibits expression of IL-1β, IL-6, IL-10, MCP-1, and TNF-α, as well as activity of horseradish peroxidase and myeloperoxidase. This compound also inhibits maturation of and antigen presentation by dendritic cells and activation and proliferation of T cells. Astilbin downregulates NF-κB and c-Myc and induces cell cycle arrest and caspase-mediated apoptosis in hepatoma cells. Additionally, astilbin also inhibits release of prostaglandin E2.

Product Info

Cas No.

29838-67-3

Purity

≥99%

Formula

C21H22O11

Formula Wt.

450.39

Chemical Name

5,7,3',4'-tetrahydroxy-2,3-dihydroflavonol-3-ß-o-rhamnoside

IUPAC Name

(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4, 5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one

Synonym

Astibin, Isoastilbin, Taxifolin 3-O-rhamnoside, Neoisoastilbin

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A7577 MSDS PDF

Info Sheet

A7577 Info Sheet PDF

References

Li P, Gao S, Jie W, et al. Astilbin inhibits proliferation of rat aortic smooth muscle cells induced by angiotensin II and down-regulates expression of protooncogene. J Huazhong Univ Sci Technolog Med Sci. 2012 Apr;32(2):181-5. PMID: 22528217.

Huang H, Cheng Z, Shi H, et al. Isolation and characterization of two flavonoids, engeletin and astilbin, from the leaves of Engelhardia roxburghiana and their potential anti-inflammatory properties. J Agric Food Chem. 2011 May 11;59(9):4562-9. PMID: 21476602.

Petacci F, Freitas SS, Brunetti IL, et al. Inhibition of peroxidase activity and scavenging of reactive oxygen species by astilbin isolated from Dimorphandra mollis (Fabaceae, Caesalpinioideae). Biol Res. 2010;43(1):63-74. PMID: 21157633.

Zou S, Shen X, Tang Y, et al. Astilbin suppresses acute heart allograft rejection by inhibiting maturation and function of dendritic cells in mice. Transplant Proc. 2010 Nov;42(9):3798-802. PMID: 21094859.

Lucas-Filho MD, Silva GC, Cortes SF, et al. ACE inhibition by astilbin isolated from Erythroxylum gonocladum (Mart.) O.E. Schulz. Phytomedicine. 2010 Apr;17(5):383-7. PMID: 19879122.

Sa F, Gao JL, Fung KP, et al. Anti-proliferative and pro-apoptotic effect of Smilax glabra Roxb. extract on hepatoma cell lines. Chem Biol Interact. 2008 Jan 10;171(1):1-14. PMID: 17996228.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P1845

    Pelitinib

    EGFR inhibitor.

    ≥98%
  • M8007

    Mubritinib, Free Base

    EGFR2 inhibitor.

    ≥99%
  • P5885

    Povidone Iodine

    Polyvinyl pyrrolidone polymer, disinfectant.

    ≥98%
  • I7478

    Istradefylline

    Adenosine A2A antagonist.

    ≥99%
  • P3469

    Pirfenidone

    Collagen synthesis inhibitor.

    ≥98%
  • C1176

    CCT-128930

    Pyrrolopyrimidine; Akt inhibitor.

    ≥98%
  • C9879

    Cytochalasin B

    Mycotoxin produced by Aspergillus; actin polyme...

    ≥98%
  • C7992

    CTX-0294885

    Bisaniline pyrimidine; pan-kinase inhibitor.

    ≥98%
  • L9701

    LY-450139

    GHS-R1a agonist, γ-secretase inhibitor.

    ≥98%
  • S9755

    (R)-Synephrine

    Synephrine is an endogenous alkaloid.

    ≥98%
  • G0182

    Gastrin Releasing Peptide, pig

    Endogenous bombesin-like peptide, involved in f...

    ≥98%
  • T6831

    Triadimenol

    Triadimefon metabolite; mutagen.

    ≥96%
  • A6264

    Apramycin Sulfate

    Aminoglycoside; protein translation inhibitor.<...

    ≥98%
  • L1780

    Levocetirizine Dihydrochloride

    L-isomer of cetirizine; histamine H1 antagonist...

    ≥98%
  • C3374

    Cisplatin

    Pt-based DNA cross-linker.

    ≥99%
  • B1653

    Benzyl Isothiocyanate

    ITC found in cruciferous vegetables.

    ≥99%
  • L0226

    Lagochiline

    Diterpene alkaloid found in Lagochilus.

    ≥98%
  • T2933

    4-Thiouridine

    Modified nucleotide used for labeling DNA; DNA ...

    ≥99%
  • C7997

    C-Type Natriuretic Peptide (1-22), human

    Endogenous cardiomodulatory peptide; NPR-B agon...

    ≥95%
  • L3453

    Linezolid

    Oxazolidinone; protein synthesis inhibitor.

    ≥99%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only