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DU-14

DU-14

Product ID D8014
Cas No. 186303-55-9
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $107.80 In stock
25 mg $471.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

DU-14 inhibits steroid sulfatase, displaying neuromodulatory, anti-amnestic, and cognition enhancing activities. DU-14 inhibits the amnestic effects of scopolamine, likely enhancing cognitive function through increasing levels of excitatory neurosteroids. In rats, DU-14 enhances memory acquisition and learning associated with contextual fear and spatial memory, but may impair memory acquisition in animals with hippocampal lesions.

Product Info

Cas No.

186303-55-9

Purity

≥98%

Formula

C22H38N2O4S

Formula Wt.

426.6

Chemical Name

(p-O-sulfamoyl)-N-tetradecanoyl tyramine

IUPAC Name

[4-[2-(tetradecanoylamino)ethyl]phenyl] sulfamate

Solubility

DMSO (25mg/ml)

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D8014 MSDS PDF

Info Sheet

D8014 Info Sheet PDF

References

Babalola PA, Fitz NF, Gibbs RB, et al. The effect of the steroid sulfatase inhibitor (p-O-sulfamoyl)-tetradecanoyl tyramine (DU-14) on learning and memory in rats with selective lesion of septal-hippocampal cholinergic tract. Neurobiol Learn Mem. 2012 Oct;98(3):303-10. PMID: 23022361.

Johnson DA, Wu T, Li P, et al. The effect of steroid sulfatase inhibition on learning and spatial memory. Brain Res. 2000 May 26;865(2):286-90. PMID: 10821934.

Johnson DA, Rhodes ME, Boni RL, et al. Chronic steroid sulfatase inhibition by (p-O-sulfamoyl)-N-tetradecanoyl tyramine increases dehydroepiandrosterone sulfate in whole brain. Life Sci. 1997;61(24):PL 355-9. PMID: 9399636.

Custom Order

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